Assistance Publique Hopitaux De Marseille

This study tests a non-invasive brain training technique called neurofeedback for people with drug-resistant epilepsy. Participants learn to change their own brain activity to reduce seizures. The study compares real neurofeedback to a sham (fake) version to see if it truly works…

This study aims to develop an artificial intelligence system that can automatically detect potential melanomas using 3D whole-body skin images. Researchers will collect scans from 1,000 adults with many moles and compare the AI's findings to those of three skin specialists. The g…

This study looks at whether a specific antibody in the blood (anti-CD146) can help doctors diagnose lung diseases caused by breathing in silica dust at work. Silica exposure can lead to serious lung problems like scarring and cancer, but there is no easy test to catch it early. R…

This study tests whether a near-infrared light device can accurately measure fat in the liver without needing a biopsy. Researchers will use the device on 90 donated livers and surgical samples to see if it can detect dangerous fat levels quickly and painlessly. If successful, it…

This study tests whether a coordinated care model—combining medical, psychological, social, and legal support—can prevent sexual violence in female asylum seekers in France. Researchers will enroll 675 women who recently applied for asylum and track them for 18 months. The goal i…

This study tests whether a spinal cord stimulator can reduce chronic nerve pain in people who have had chemotherapy. The device sends mild electrical pulses to the spinal cord to block pain signals. Sixty-eight adults with pain lasting at least a year will receive both active and…

This study compares a joint consultation with a lung doctor (pulmonologist) and an ear-nose-throat (ENT) specialist against separate visits for adults with asthma and chronic sinusitis with nasal polyps. The main goal is to see if the combined approach reduces the need for oral s…

This study tests a slow-release melatonin (PedPRM) in 120 children aged 6 to 18 who have anorexia nervosa and trouble sleeping. Participants take either melatonin or a placebo for 13 weeks. The goal is to see if it safely improves total sleep time and related symptoms like anxiet…

This study will collect blood and swab samples from 160 adults with solid tumors who are about to start immunotherapy. The goal is to find a biological 'signature' that can predict which patients will develop severe immune-related side effects. If such a signature is found, it co…

This study will follow 45 people with drug-resistant focal epilepsy who are already scheduled for a brain procedure called SEEG-guided thermocoagulation. Researchers will use MRI scans, brain recordings, and blood tests before and after treatment to find markers that predict whet…

This study aims to create better MRI methods for looking at the brains of people with multiple sclerosis (MS). Researchers will test these methods on 272 healthy volunteers and MS patients using both standard (3 Tesla) and ultra-high-field (7 Tesla) MRI machines. The goal is to m…

This study aims to better understand changes in the mouth's tiny organisms (dysbiosis) in people over 60 or with weakened immune systems. Researchers will collect dental plaque and saliva samples from 250 participants to see how common these changes are and whether a simple saliv…

This study will look at lung tissue, blood, and fluid samples from 105 adults having lung surgery to understand how pulmonary hypertension (high blood pressure in the lungs) develops in people with chronic lung disease. Participants are split into three groups: those with lung di…

This study looks at how Gamma Knife radiosurgery affects brain connections in people with severe facial pain called trigeminal neuralgia. About 28 adults will get brain scans before treatment and at 1, 3, and 12 months after. The goal is to see if changes in brain wiring match pa…

This study looks at 50 adults with primary central nervous system lymphoma who are receiving high-dose methotrexate, a key chemotherapy. The goal is to see if measuring the drug early in the blood can predict later kidney problems. By identifying at-risk patients sooner, doctors …

This study looks at whether teenagers with severe scoliosis have trouble sensing where their body is in space (proprioception). Researchers will compare brain scans and muscle measurements of 60 teens with scoliosis to healthy controls. The goal is to understand if these issues a…

This study will follow 100 adults who need a stoma (an opening in the belly to pass waste). It compares those who get education and stoma site marking before surgery to those who do not. The goal is to see if this preparation improves quality of life and reduces early problems li…

This study checks if physiotherapists get chemotherapy drugs inside their bodies after treating patients who recently received these drugs. Twenty physiotherapists will provide urine and skin samples before and after giving massages or other hands-on care. The goal is to understa…

This study aims to develop a simple blood test that checks how well a person's immune cells can fight blood cancer. Researchers will collect blood samples from 166 adults with blood cancers to measure immune cell activity and look at genetic factors. The goal is to create a test …

This study follows 75 young adults with severe hemophilia who were part of an earlier study as teens. Researchers want to see if their healthcare habits change as they become adults and what factors help them stick to treatment. The goal is to understand how to support a smooth t…