Brain training offers hope for epilepsy patients who Don't respond to drugs
NCT ID NCT07356661
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a non-invasive brain training technique called neurofeedback for people with drug-resistant epilepsy. Participants learn to change their own brain activity to reduce seizures. The study compares real neurofeedback to a sham (fake) version to see if it truly works. 22 adults with at least 3 seizures per month will take part.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 22 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 18 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
For patients : Inclusion Criteria: * Male or female patient between 18 and 65 years old * Patient suffering from focal or multifocal drug-resistant epilepsy * Patient having a number of seizures: at least 3 / month during the baseline * Patient's IQ, which in the investigator's opinion will enable questionnaires and neuropsychological assessments to be carried out; * Patient having stable medications for epilepsy 4 weeks before the baseline (except rescue treatment); * Patient able to understand, speak and write in French; * Patient willing to participate, and gave written consent to the study after receiving clear information * Patient beneficiary or affiliated to a health insurance plan Exclusion Criteria: * \- Difficulty reading or understanding the French language or inability to understand information about the study * Generalized epilepsy * Major visual impairment incompatible with the realization of neurofeedback, based on investigator's opinion. * Patient currently having psychogenic non-epileptic seizures * Any condition that makes the study subject, in the opinion of the investigator, unsuitable for the study including presence of any disease, abnormality, medical or physical condition that, in the opinion of the investigator, may adversely impact, compromise, interfere, limit, affect or reduce the safety of the subject, the integrity of the data ; Person protected by articles L1121-5, L1121-6 of Public Health Code (pregnant or breastfeeding woman, deprived of liberty by judicial decision, situations of social fragility, adults unable or unable to express their consent, person under judicial safeguard (article L1122-2)). For healthy volunteers : Inclusion criteria : * Male or female of over 18 years of age * IQ compatible with the realization of the study * Patient able to understand, speak and write in French; * Patient willing to participate, and gave written consent to the study after receiving clear information * Subject beneficiary or affiliated to a health insurance plan Exclusion criteria : * Subject presenting any neurological or psychiatric illnesses. * Subject having major visual impairment incompatible with the realization of neurofeedback, based on investigator's opinion.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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