New MRI techniques could sharpen view of MS brain damage
NCT ID NCT07245589
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to create better MRI methods for looking at the brains of people with multiple sclerosis (MS). Researchers will test these methods on 272 healthy volunteers and MS patients using both standard (3 Tesla) and ultra-high-field (7 Tesla) MRI machines. The goal is to make scans faster, more reliable, and better at detecting MS-related changes, which could help doctors diagnose and track the disease more accurately.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 272 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Nov 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 52 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * For healthy volunteers : * Male or female aged 20 to 50 * Subject with no history of previous or concomitant neurological and psychiatric diseases at the time of inclusion * Subject without a history of traumatic brain injury * Subject with no vascular history (arterial hypertension, stroke) or concomitant at the time of its inclusion * Subject has no history of chronic drug and/or alcohol abuse * Subject having received information regarding the study and having signed an informed consent * Beneficiary or entitled person to a social security scheme * For MS patients * Male or female aged 18 to 52 * Patient diagnosed with MS according to the * criteria of McDonald 2017 * Patient presenting a maximum EDSS of 6 * Patient with MS for less than 10 years of evolution * Patient having received information regarding the study and having signed an informed consent * Patient beneficiary or entitled to a plan of social security Exclusion Criteria: * For healthy subjects : * Subject presenting a contraindication to performing an MRI: pacemaker, presence of metal implants, claustrophobia. * Subject unable to maintain a supine position for a prolonged period * Subject in a period of exclusion from another research protocol at the time of signing consent/non-opposition form * Subjects covered by articles L1121-5 to 1121-8 of the Public Health Code (minor patient, adult patient under guardianship or curatorship, patient deprived of liberty, pregnant or breastfeeding woman) * For MS patients * Subject presenting a contraindication to performing an MRI: pacemaker, presence of metal implants, claustrophobia. * Subject unable to maintain a supine position for a prolonged period * Subject in a period of exclusion from another research protocol at the time of signing consent/non-opposition form * Subjects covered by articles L1121-5 to 1121-8 of the Public Health Code (minor patient, adult patient under guardianship or curatorship, patient deprived of liberty, pregnant or breastfeeding woman)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hôpital Gui de Chauliac
Montpellier, France
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Other studies related to the condition(s) this trial covers.
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