New light scanner could replace liver biopsies for transplant patients
NCT ID NCT07254533
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a near-infrared spectroscopy device that scans the liver with light to diagnose and measure fatty liver disease. Researchers aim to see if it can accurately detect fat levels above 5% and 30%, which are important for liver transplant decisions. The study will include 90 liver grafts and surgical samples from adults. If it works, this non-invasive tool could replace the current biopsy method, which is invasive and can vary between doctors.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- near-infrared spectrometer
- What this could lead to
- If successful, this could provide a quick, non-invasive way to measure liver fat, helping doctors decide which donor livers are safe to transplant.
- What could go wrong
- This is an early-stage study with only 90 participants, and the device may not be accurate enough to replace current biopsy methods.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Liver grafts: * Men or women aged 18 and over * All donors accepted by the MA4FC procurement team, including brain-dead donors and Maastricht 3 donors, even if placed on a perfusion machine * Donors whose families have received information about the study and have not expressed any opposition Surgical specimens (hepatectomy): * Men or women aged 18 years and older * Subjects who have undergone surgery for any indication of hepatectomy * Affiliated with social security, * Having received information about the study and not having expressed opposition Exclusion Criteria: Liver grafts: * Donors whose liver will be subject to a SPLIT procedure * Donors for whom there is a medical-legal obstacle * Donors whose family or loved ones oppose scientific sampling: The hospital coordination team will consult the national refusal register and question loved ones to determine whether the deceased would have opposed sampling. If the donor and/or family oppose scientific sampling, then sampling will not be performed. Surgical specimens (hepatectomy): * Subjects covered by Articles L1121-5 to 1121-8 of the Public Health Code (minors, adults under guardianship or curatorship, patients deprived of their liberty, pregnant or breastfeeding women), * Subjects who do not understand the French language
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Timone Hospital
Marseille, 13005, France
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