POSTTRAUMATIC STRESS DISORDER
Clinical trials for POSTTRAUMATIC STRESS DISORDER explained in plain language.
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Sleep therapy may protect PTSD hearts
Disease control CompletedThis study investigated whether treating insomnia could reduce the risk of heart disease in people with PTSD. Researchers enrolled 140 adults with both PTSD and insomnia to test an 8-week sleep therapy program. They measured changes in blood pressure, blood vessel function, and o…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Duke University • Aim: Disease control
Last updated Apr 04, 2026 00:21 UTC
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Kenya trial finds path to mental health care without specialists
Disease control CompletedThis study tested two different first-line treatments for depression and PTSD—talk therapy (Interpersonal Psychotherapy) and a common antidepressant (fluoxetine)—when delivered by trained non-specialist health workers in a Kenyan primary care clinic. It aimed to find the most eff…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Apr 04, 2026 00:20 UTC
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Can getting busy help veterans drink less and heal from trauma?
Disease control CompletedThis study tested two different talk therapy approaches for U.S. military veterans dealing with both alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD). Ten veterans received eight sessions of either Behavioral Activation, which focuses on increasing rewarding, a…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: RTI International • Aim: Disease control
Last updated Apr 04, 2026 00:20 UTC
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New approach aims to help veterans with PTSD reclaim their lives
Disease control CompletedThis study tested a personalized version of a standard talk therapy for PTSD, called Cognitive Processing Therapy (CPT). It involved 179 Veterans and aimed to see if tailoring the therapy to address each person's specific life challenges—like work, relationships, or other stresso…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Neck injection could boost PTSD therapy success
Disease control CompletedThis study tested if adding a simple neck injection to a standard PTSD therapy could make the therapy work better. Researchers compared the standard therapy alone to the therapy combined with either a real or a fake (placebo) injection. The goal was to see if the combination coul…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Brain wave therapy tested as new PTSD treatment
Disease control CompletedThis study tested whether a personalized magnetic brain stimulation therapy could help reduce symptoms of Post-Traumatic Stress Disorder (PTSD). 158 adults with PTSD received either the real treatment or a placebo version for 5 weeks, with neither participants nor doctors knowing…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Wave Neuroscience • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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New text & video program aims to shield assault survivors from PTSD and opioid misuse
Prevention CompletedThis study tested a new support program for adults who recently experienced sexual assault. Researchers developed a brief video to watch during a medical exam and follow-up text messages for the next month. The goal was to see if this approach could help prevent the development o…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Prevention
Last updated Mar 16, 2026 15:24 UTC
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Video game helps moms erase traumatic birth memories
Symptom relief CompletedThis study tested whether a single therapy session could reduce distressing memories of childbirth. Mothers who experienced intrusive traumatic memories after giving birth were asked to briefly recall their birth experience and then play the video game Tetris. Researchers compare…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Centre Hospitalier Universitaire Vaudois • Aim: Symptom relief
Last updated Apr 04, 2026 00:20 UTC
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New hope for Veterans' PTSD: Hormone-Based treatment shows promise
Symptom relief CompletedThis study tested whether pregnenolone, a natural hormone, could help reduce PTSD symptoms in Iraq/Afghanistan-era veterans. Over 10 weeks, 96 veterans with PTSD received either pregnenolone or a placebo pill while continuing their regular medications. Researchers measured change…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: PHASE2 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Apr 04, 2026 00:19 UTC
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New hope for healing trauma after spinal cord injury
Symptom relief CompletedThis study tested whether a specific talk therapy could help people with spinal cord injuries who also have post-traumatic stress disorder (PTSD). Researchers enrolled 30 participants and randomly assigned them to either receive the new therapy or continue with their usual care. …
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated Apr 03, 2026 14:41 UTC
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Can focusing on the positive help teens heal from trauma and ADHD?
Symptom relief CompletedThis study tested a new group therapy approach for teenagers who have both Attention Deficit Hyperactivity Disorder (ADHD) and Post-Traumatic Stress Disorder (PTSD). The therapy, called Reminder-Focused Positive Psychiatry, aims to build resilience and well-being by focusing on p…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated Apr 03, 2026 14:41 UTC
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New app aims to heal the hidden wounds after a Child's injury
Symptom relief CompletedThis study tested a mobile app called CAARE, designed to help children and their parents with the emotional and behavioral stress that often follows a serious injury. The app provided support and resources to improve mental health and quality of life for families. Researchers wor…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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Can training a service dog heal invisible wounds? military study investigates
Symptom relief CompletedThis study looked at whether learning to train a future service dog, combined with standard medical care, could help reduce symptoms of post-traumatic stress (PTS) and post-concussive symptoms in military members. Researchers enrolled 156 participants to measure changes in stress…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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VA study tests One-Size-Fits-All therapy against standard treatments
Symptom relief CompletedThis study compared two types of talk therapy for veterans with PTSD, depression, or panic disorder. Researchers tested if a single, streamlined therapy could work as well as separate, disorder-specific therapies. 304 veterans received 12 weeks of either the new combined approach…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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New hope for Veterans' PTSD brain fog: training program shows promise
Symptom relief CompletedThis small pilot study tested whether a thinking skills training program could help veterans with PTSD who still struggle with memory, focus, and concentration after standard PTSD therapy. Researchers worked with 21 veterans to see if the training was practical and acceptable, an…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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New program aims to help pregnant moms and their babies after violence
Symptom relief CompletedThis study tested a special support program for pregnant women who have recently experienced violence from a partner. The program aimed to help improve the mothers' mental health, reduce their risk of further violence, and support better parenting and infant development. Research…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: University of Notre Dame • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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Could sensory differences predict PTSD in soldiers?
Knowledge-focused CompletedThis study investigated whether having sensory processing differences makes a person more vulnerable to developing PTSD symptoms after experiencing trauma. Researchers showed combat-related movie clips to 248 healthy young adults, some with and some without sensory issues, and me…
Matched conditions: POSTTRAUMATIC STRESS DISORDER
Phase: NA • Sponsor: Tel Aviv University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC