Could a brain steroid help veterans with PTSD?
NCT ID NCT03799562
First seen Jan 16, 2026 · Last updated Jun 18, 2026 · Updated 22 times
Summary
This study tested whether a natural brain chemical called pregnenolone can reduce PTSD symptoms in Iraq and Afghanistan veterans. 96 veterans with PTSD took either pregnenolone or a placebo for 10 weeks and had their symptoms checked regularly. The goal was to see if the supplement could ease PTSD and related issues like pain.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Durham VA Medical Center, Durham, NC
Durham, North Carolina, 27705-3875, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
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