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Could a brain steroid help veterans with PTSD? new study explores

NCT ID NCT03799562

First seen Jan 16, 2026 · Last updated Apr 29, 2026 · Updated 13 times

Summary

This study tested whether a natural brain chemical called pregnenolone can reduce PTSD symptoms in 96 Iraq/Afghanistan-era veterans. Over 10 weeks, participants took either pregnenolone or a placebo and completed mental and physical health checkups. The goal was to see if this supplement could ease PTSD and related issues like pain.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Durham VA Medical Center, Durham, NC

    Durham, North Carolina, 27705-3875, United States

Conditions

Explore the condition pages connected to this study.