OBSESSIVE-COMPULSIVE DISORDER

This study looks at whether adding cognitive behavioral therapy (a type of talk therapy) to standard medication can improve symptoms and daily functioning for people with conditions like anxiety, depression, OCD, PTSD, bipolar disorder, schizophrenia, and personality disorders. A…

This study tests a brain implant (deep brain stimulation) in 2 people with severe obsessive-compulsive disorder (OCD) that hasn't improved with standard treatments. The device sends electrical pulses to specific brain areas to help control symptoms. The goal is to reduce OCD seve…

This early-stage study tests whether psilocybin, the active ingredient in magic mushrooms, given alongside psychotherapy can safely reduce symptoms in people with obsessive-compulsive disorder (OCD) that hasn't responded to standard treatments. Ten adults will receive two 25 mg d…

This study tests whether tolcapone, a drug currently used for Parkinson's disease, can safely reduce symptoms in adults with moderate to severe obsessive-compulsive disorder (OCD). About 49 participants will receive either tolcapone or a placebo to compare changes in OCD severity…

This study looked at whether measuring brain inflammation with scans and blood tests could predict how much people with obsessive-compulsive disorder (OCD) would benefit from adding the anti-inflammatory drug celecoxib to their current medication. The goal was to see if a persona…

This early-stage study is testing whether repeated doses of psilocybin, the active ingredient in magic mushrooms, can reduce symptoms of obsessive-compulsive disorder (OCD). The trial involves 30 adults with severe OCD who have not responded well to standard treatments. Researche…

This study looks at whether unlicensed professionals can successfully give cognitive behavioral therapy (CBT) to patients in a general hospital. About 250 adults with conditions like anxiety, depression, OCD, or PTSD will take part. The goal is to see if this approach improves ps…

This study explores whether a new type of group therapy, called natural psychotherapy, can help people with anxiety disorders. Sixty adults aged 15 to 55 with obsessive-compulsive disorder will take part. The therapy is based on Eastern culture and aims to reduce anxiety symptoms…

This study tests if a non-invasive brain stimulation technique called TMS can improve the effects of exposure therapy for teens and young adults with OCD. Fifty participants aged 12 to 21 will receive either real or fake TMS before therapy sessions for two weeks. Researchers will…

This study tests a non-invasive brain stimulation method called tDCS for people with obsessive-compulsive disorder (OCD) who haven't gotten better with standard treatments like therapy or antidepressants. About 43 participants will receive low-level electrical current through ele…

This early-phase study tests whether psilocybin, the active ingredient in magic mushrooms, can safely help reduce symptoms of obsessive-compulsive disorder (OCD). Thirty-five adults with OCD who have not responded well to standard treatments will receive psilocybin in a controlle…

This study tests whether a short mindfulness program can reduce the distress of obsessive-compulsive disorder (OCD). About 420 adults with OCD will receive either mindfulness training or standard therapy. Researchers will measure changes in OCD symptoms and explore how mindfulnes…

This study was designed to find better ways to place deep brain stimulation (DBS) electrodes in patients with severe obsessive-compulsive disorder (OCD). The goal was to use brain scans to personalize targeting and improve symptom relief. However, the study was withdrawn before e…

This study from Stanford University looks at whether brain imaging can identify different types of OCD and predict how well patients respond to a non-invasive brain stimulation treatment called rTMS. Researchers will test two different brain targets in 212 adults with moderate to…

This study looks at 60 people with obsessive-compulsive disorder (OCD) who either respond well to medication or brain stimulation, or don't respond at all. Researchers will take blood samples and turn them into nerve cells in the lab to study how these cells react to treatments. …

This study watches 192 teens aged 12–20 who are already getting therapy for anxiety, depression, or OCD. Researchers will compare Cognitive Behavioral Therapy (CBT) and Brief Strategic Therapy (BST) to see which helps more with symptoms, self-esteem, and quality of life. No new t…

This study explores whether a single type of therapy (transdiagnostic CBT) can work as well as different therapies tailored to specific anxiety disorders like panic disorder or social anxiety. Researchers will check if it's possible to run a larger trial by looking at how many pe…

This study is for people with severe, hard-to-treat OCD. Researchers are testing an advanced brain stimulation system that can adapt to a person's needs. The goal is to find brain signals linked to OCD distress and improve how deep brain stimulation works. Only 2 people will take…

This study is for people with severe, hard-to-treat obsessive-compulsive disorder (OCD). Researchers are testing a new type of deep brain stimulation that uses the brain's own signals to automatically adjust the electrical pulses. The goal is to improve symptom control and reduce…