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Can mindfulness beat OCD? large trial aims to find out

NCT ID NCT04914923

First seen Mar 06, 2026 · Last updated Jun 23, 2026 · Updated 15 times

Summary

This study tests whether mindfulness-based therapy can help people with obsessive-compulsive disorder (OCD). Researchers will compare mindfulness to standard cognitive behavioural therapy (CBT) in 420 adults with OCD. The goal is to see if mindfulness reduces OCD symptoms and to understand how it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • St. Joseph's Healthcare Hamilton

    Hamilton, Ontario, L8N 4A6, Canada

  • Sunnybrook Health Sciences Centre

    Toronto, Ontario, M4N 3M5, Canada

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Mindfulness-Based Cognitive Therapy (MBCT) and Cognitive Behaviour Therapy (CBT)

What this could lead to

If it works, this could offer a new, non-drug treatment option for OCD that helps reduce symptoms and improve quality of life.

What could go wrong

This is a mid-stage study, and previous small studies have shown mixed results. It may not prove more effective than existing therapies, and benefits may vary.

Conditions

The condition(s) this trial relates to.

obsessive-compulsive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.