OBSESSIVE-COMPULSIVE DISORDER

This study is testing whether a surgically implanted brain stimulation device can help people with severe obsessive-compulsive disorder (OCD) that hasn't responded to other treatments. Ten participants will have a device implanted that can both stimulate the brain and record its …

This study aims to understand and potentially treat the unusual sensory feelings that often drive compulsive behaviors in people with Obsessive-Compulsive Disorder (OCD). Researchers will use brain scans and a non-invasive magnetic stimulation technique (rTMS) on a specific brain…

This study is testing whether focused ultrasound can safely reduce symptoms of obsessive-compulsive disorder (OCD) in people who haven't improved with standard treatments like therapy and medications. Researchers will use MRI-guided sound waves to target a specific brain area wit…

This is a small, early-stage study to see if deep brain stimulation (DBS) can help people with severe obsessive-compulsive disorder (OCD) that hasn't improved with other treatments. Four participants will have a device implanted to deliver mild electrical pulses to two different …

This study is testing whether psilocybin, the active compound in 'magic mushrooms,' can help people with OCD when standard treatments haven't worked well enough. Twenty adults with moderate to severe OCD will be randomly assigned to receive either a low or high dose of psilocybin…

This study is testing whether a medication called valbenazine can safely reduce symptoms in adults with moderate to severe obsessive-compulsive disorder (OCD). Thirty participants will take the drug or a placebo for six weeks each, with a break in between, to see which is more ef…

This study aims to see if briefly triggering a person's obsessive-compulsive symptoms right before a gentle brain stimulation treatment makes the treatment work better. Researchers will compare two groups of adults with severe, treatment-resistant OCD: one receiving only the brai…

This study is testing a free, one-time online program designed to help caregivers of children with OCD. The program teaches caregivers how to reduce stress and avoid behaviors that accidentally make OCD symptoms worse. Researchers want to see if this brief, accessible approach wo…

This study aims to test a culturally adapted self-help workbook for obsessive-compulsive disorder (OCD) in Pakistan, where access to trained therapists is limited. The workbook is based on cognitive behavioral therapy (CBT) principles and includes guidance from a therapist. Resea…

This study aims to understand how common obsessive-compulsive symptoms are in people recovering from substance use problems. Researchers will compare 51 adults with substance use disorder to 51 healthy adults, using questionnaires and interviews to measure symptoms. The goal is t…