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Could two weeks of therapy beat six months for anxiety?

NCT ID NCT05942391

Symptom relief Sponsor: Amsterdam UMC, location VUmc Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a short, intensive course of cognitive behavioral therapy (CBT) over 2 weeks works better than the usual weekly sessions over 6 months for people with anxiety disorders. 120 adults with conditions like panic disorder, OCD, or PTSD will be randomly assigned to one of the two treatments. The goal is to see which approach improves daily functioning faster and more effectively.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cognitive behavioral therapy (CBT) - exposure therapy
What this could lead to
If it works, this could offer a faster, more effective treatment option for anxiety disorders, helping people return to normal life in weeks instead of months.
What could go wrong
This is a relatively small trial (120 people) and the intensive format may not suit everyone. Results may not apply to all anxiety types or real-world settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2024

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Age 18 years or older; Reaching out for mental health care for one of the following disorders: panic disorder, agoraphobia, generalised anxiety disorder, social anxiety disorder, posttraumatic stress disorder, obsessive-compulsive disorder, health anxiety disorder. Exclusion Criteria: * Is in need of emergency mental health care * Has insufficient language skills in Dutch * Has evident cognitive limitations * Has had changes in the use of medication during the last 3 months.

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Conditions

The condition(s) this trial relates to.

agoraphobia anxiety disorder generalized anxiety disorder hypochondriasis injury obsessive-compulsive disorder panic disorder post-traumatic stress disorder social phobia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety disorders Hypochondriasis Obsessive compulsive disorder Posttraumatic stress disorder

Contacts and locations

Locations

  • Altrecht Academisch Angstcentrum

    Utrecht, Netherlands

  • GGZ Centraal, Algemeen Specialistische Polikliniek

    Hilversum, Netherlands

  • GGZ inGeest, polikliniek Angst & Dwang, locatie Amstelmere

    Amstelveen, Netherlands

  • GGZ inGeest, polikliniek Angst & Dwang, locatie De Nieuwe Valerius

    Amsterdam, Netherlands

  • GGZ inGeest, polikliniek Angst & Dwang, locatie Spaarnepoort

    Hoofddorp, Netherlands

  • GGZ inGeest, polikliniek Angst & Dwang, locatie Zuiderpoort

    Haarlem, Netherlands

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