Amsterdam Umc, Location Vumc

This study is testing if a newer drug called sotatercept can improve how well the heart pumps in people with pulmonary arterial hypertension (PAH), a serious lung and heart condition. Twenty adult patients with PAH will receive injections of sotatercept for 24 weeks. Researchers …

This study is testing if using a temporary mechanical heart pump during a complex artery-opening procedure is safer for patients with weak hearts. The pump is inserted to help the heart function while doctors place a stent to clear a major blockage. Researchers want to see if thi…

This study is testing if adding the anti-inflammatory drug celecoxib to standard depression treatment works better than a placebo for a specific group of patients. It focuses on people with 'Immuno-Metabolic Depression,' a type linked to inflammation, weight gain, and extreme fat…

This study is testing a new three-part treatment for patients with pancreatic cancer that can be surgically removed. Before surgery, patients receive a combination of chemotherapy, immunotherapy, and targeted radiation. The goal is to see if this intensive approach helps control …

This study is testing whether giving a single, precise dose of radiation before a second lumpectomy can help women with recurrent breast cancer. The approach aims to shrink tumors while reducing side effects and preserving breast appearance better than traditional methods. Resear…

This study aims to find the best way to treat breast cancer that has returned in the breast or nearby lymph nodes after initial treatment. It will follow 500 patients who receive standard repeat radiation, with or without added heat therapy (hyperthermia), to see which approach b…

This study is testing whether a non-invasive brain stimulation technique, called repetitive transcranial magnetic stimulation (rTMS), can help adults with severe obsessive-compulsive disorder (OCD) who have not gotten better with standard exposure therapy. Participants will recei…

This project aims to help teens in vulnerable urban areas develop healthier habits by letting them lead the way. Adolescents in Denmark, the Netherlands, Nigeria, and South Africa will work with researchers and local leaders to design and test changes to their neighborhoods. The …

This study is testing a wearable leg device called Cue2Walk that aims to help people with Parkinson's disease who experience 'freezing of gait'—a sudden, temporary inability to move their feet forward. The device automatically detects these freezing episodes and provides rhythmic…

This study is testing whether a 12-week exercise program called 'MegaPower training' can help children with cerebral palsy walk better and participate more in daily activities like playing with friends. Researchers will compare the exercise program to the children's usual care to…

This study is testing whether a gentle, non-invasive brain stimulation treatment can reduce severe fatigue and thinking problems in people with long COVID. Researchers will compare a real magnetic stimulation treatment to a fake one in 66 adults to see if it helps. They will also…