OBESITY AND OVERWEIGHT
Clinical trials for OBESITY AND OVERWEIGHT explained in plain language.
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New weekly shot shows promise for weight loss in early trial
Disease control CompletedThis study tested a new medicine called MET097, given as a weekly injection, to see if it is safe and helps with weight loss in adults who are overweight or have obesity but are otherwise healthy. About 120 people took part, receiving either the drug or a placebo for up to 12 wee…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: PHASE1, PHASE2 • Sponsor: Metsera, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated May 26, 2026 03:24 UTC
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Could a polyphenol drink help shed pounds? new study investigates
Disease control CompletedThis study tested whether a special polyphenol-enriched product can help people who are overweight or obese lose weight and body fat. About 70 adults with a BMI between 25 and 35 took the product or a placebo for a period of time. Researchers measured changes in weight, fat mass,…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Carmen Lucas Abellán • Aim: Disease control
Last updated May 26, 2026 03:17 UTC
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Can a simple supplement melt belly fat? new study says maybe.
Disease control CompletedThis study tested whether a supplement called BK329 can help reduce body fat in adults who are overweight or obese. One hundred participants took either BK329 or a placebo for 12 weeks. Researchers measured changes in total body fat, weight, and waist size to see if the supplemen…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Pusan National University Yangsan Hospital • Aim: Disease control
Last updated May 26, 2026 03:11 UTC
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Which diet plan works best? new study puts weight loss programs to the test
Disease control CompletedThis study looked at how well three different commercial weight loss programs help adults with overweight or obesity lose weight. About 459 people took part, and researchers measured how much weight they lost after 12 weeks. The goal was to see which program works best for short-…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: WW International Inc • Aim: Disease control
Last updated May 26, 2026 02:48 UTC
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New weight loss drug HDM1005 shows promise in early safety trial
Disease control CompletedThis early-stage study tested a new drug called HDM1005 in 65 healthy adults to see if it is safe and how the body processes it. Participants received either the drug or a placebo as a single shot. The study also looked at changes in weight and other health markers. The goal is t…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: PHASE1 • Sponsor: Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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Rice swap shows promise for prediabetes in small study
Disease control CompletedThis study looked at whether eating sorghum rice instead of white rice for one week could improve health markers in people with prediabetes. Twenty-six police officers with prediabetes were split into two groups: one ate sorghum rice, the other white rice. Researchers measured ch…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Dr. Soetomo General Hospital • Aim: Disease control
Last updated May 07, 2026 18:38 UTC
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AI-Powered Self-Help helps nurses curb emotional eating
Symptom relief CompletedThis study tested whether a ChatGPT-supported online group program could help overweight female nurses manage emotional and uncontrolled eating. 44 nurses participated in online sessions guided by a facilitator with AI support. The goal was to improve eating behaviors and body im…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Dokuz Eylul University • Aim: Symptom relief
Last updated May 26, 2026 03:04 UTC
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Calorie cutting may switch on genes that control fat and appetite
Knowledge-focused CompletedThis study looked at how a low-calorie diet changes the activity of two genes (SIRT1 and leptin receptor) in white blood cells of 60 adults who are overweight and have high triglycerides. Researchers measured these gene changes along with blood fats, hormones, and inflammation ma…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Shahid Beheshti University of Medical Sciences • Aim: Knowledge-focused
Last updated May 26, 2026 03:11 UTC
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Calorie labels on drinks: a new way to cut down on booze?
Knowledge-focused CompletedThis study looked at whether showing calorie information on alcohol products or changing serving sizes could help people drink less. Over 300 adults who drink regularly took part in a real-world pub quiz experiment. Researchers measured how much alcohol and calories they consumed…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: University of Liverpool • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Sleeve gastrectomy alters appetite hormone levels, small study finds
Knowledge-focused CompletedThis study looked at 36 adults with severe obesity who had laparoscopic sleeve gastrectomy, a type of weight-loss surgery. Researchers measured blood levels of Phoenixin-14, a hormone that may affect appetite, before and after surgery. The goal was to see if the surgery changes t…
Matched conditions: OBESITY AND OVERWEIGHT
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Processed food shock: even one meal can spike your stress hormone!
Knowledge-focused CompletedThis study looked at how eating ultra-processed foods versus unprocessed foods affects the body's stress hormone, cortisol. Twenty healthy men ate two different meals with similar calories and nutrients, and researchers measured their blood cortisol levels before and after eating…
Matched conditions: OBESITY AND OVERWEIGHT
Phase: NA • Sponsor: Eleonora Seelig • Aim: Knowledge-focused
Last updated May 19, 2026 11:48 UTC