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Berry and green tea extracts tested for weight loss in new study

NCT ID NCT06911346

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 01, 2026 · Updated 2 times

Summary

This study tests whether eating more plant-based foods or taking polyphenol supplements (like green tea and berry extracts) can help overweight adults lose weight and improve heart health. 99 participants will follow a calorie-restricted diet for 12 weeks, with one group eating extra fruits and nuts, another taking polyphenol supplements, and a control group getting a placebo. Researchers will measure weight, blood pressure, and blood markers to see if these approaches work.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Polyphenol-rich foods and supplements (plant extracts from maqui, green tea, olive leaf, cranberry, grape, plus apple, blueberries, hazelnuts, olive oil, coffee)
What this could lead to
If it works, this could point toward a simple dietary strategy to help manage weight and lower heart disease risk.
What could go wrong
This is a small, early-stage trial with only 99 participants over 12 weeks. Results may not apply to everyone, and the supplements may not work better than a healthy diet alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Jul 2025

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 25 and 45 years (adult) * Sexes: All * Overweight or obesity class I (BMI 25-35 kg/m²) * At least three of the following cardiometabolic risk factors: Current smoker (more than 1 cigarette per day during the last month) Sitting time greater than 7 hours per day or classified as inactive according to the IPAQ Fasting glucose ≥100 mg/dL (5.6 mmol/L) High blood pressure: Systolic blood pressure \>130 mmHg Diastolic blood pressure \>85 mmHg High serum triglycerides (≥150 mg/dL) HbA1c ≥38 mmol/mol (\>5.7%) Waist circumference defined by Peterman et al. for the Chilean population: 92.3 cm for men 87.6 cm for women High high-sensitivity C-reactive protein (hs-CRP) (≥2.0 mg/L) Family history of premature coronary heart disease: Definite myocardial infarction or sudden death before age 55 in father or male first-degree relative Before age 65 in mother or female first-degree relative Exclusion Criteria: * Presence of cardiovascular disease, diabetes, or hypertension * Severe medical conditions that may impair participation in a nutrition intervention study (e.g., digestive disease, advanced malignancy, major neurological or psychiatric disease) * Any medical condition limiting survival to less than one year * Illegal drug use, chronic alcoholism, or problematic alcohol use * BMI ≥35 kg/m² * Antibiotic use within the last month * Low predicted likelihood of changing dietary habits according to the Prochaska and DiClemente stages of change model

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fabian Lanuza

    Temuco, Araucania, 4780000, Chile

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Other studies related to the condition(s) this trial covers.