Berry and green tea extracts tested for weight loss in new study
NCT ID NCT06911346
First seen Jun 27, 2026 · Last updated Sep 01, 2026 · Updated 2 times
Summary
This study tests whether eating more plant-based foods or taking polyphenol supplements (like green tea and berry extracts) can help overweight adults lose weight and improve heart health. 99 participants will follow a calorie-restricted diet for 12 weeks, with one group eating extra fruits and nuts, another taking polyphenol supplements, and a control group getting a placebo. Researchers will measure weight, blood pressure, and blood markers to see if these approaches work.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Polyphenol-rich foods and supplements (plant extracts from maqui, green tea, olive leaf, cranberry, grape, plus apple, blueberries, hazelnuts, olive oil, coffee)
- What this could lead to
- If it works, this could point toward a simple dietary strategy to help manage weight and lower heart disease risk.
- What could go wrong
- This is a small, early-stage trial with only 99 participants over 12 weeks. Results may not apply to everyone, and the supplements may not work better than a healthy diet alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
100 people
The number who actually took part.
- Started
-
Jul 2025
- Finished
-
Aug 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
25 to 45 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 25 and 45 years (adult) * Sexes: All * Overweight or obesity class I (BMI 25-35 kg/m²) * At least three of the following cardiometabolic risk factors: Current smoker (more than 1 cigarette per day during the last month) Sitting time greater than 7 hours per day or classified as inactive according to the IPAQ Fasting glucose ≥100 mg/dL (5.6 mmol/L) High blood pressure: Systolic blood pressure \>130 mmHg Diastolic blood pressure \>85 mmHg High serum triglycerides (≥150 mg/dL) HbA1c ≥38 mmol/mol (\>5.7%) Waist circumference defined by Peterman et al. for the Chilean population: 92.3 cm for men 87.6 cm for women High high-sensitivity C-reactive protein (hs-CRP) (≥2.0 mg/L) Family history of premature coronary heart disease: Definite myocardial infarction or sudden death before age 55 in father or male first-degree relative Before age 65 in mother or female first-degree relative Exclusion Criteria: * Presence of cardiovascular disease, diabetes, or hypertension * Severe medical conditions that may impair participation in a nutrition intervention study (e.g., digestive disease, advanced malignancy, major neurological or psychiatric disease) * Any medical condition limiting survival to less than one year * Illegal drug use, chronic alcoholism, or problematic alcohol use * BMI ≥35 kg/m² * Antibiotic use within the last month * Low predicted likelihood of changing dietary habits according to the Prochaska and DiClemente stages of change model
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Obesity and overweight are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Fabian Lanuza
Temuco, Araucania, 4780000, Chile
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New injection IBI3046 tested for weight management
- One-Size-Fits-All diets may be outdated: personalized plans put to the test
- Can timing your carbs tame metabolic risk?
- Home visits may boost heart health for pregnant women in nigeria
- Could a diabetes drug protect obese Teens' hearts?
- Could a biweekly shot rival weekly Weight-Loss drugs?