Sleeve surgery may alter appetite hormone levels
NCT ID NCT07004556
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 36 adults with severe obesity who had laparoscopic sleeve gastrectomy, a type of weight-loss surgery. Researchers measured blood levels of a hormone called Phoenixin-14, which is thought to influence appetite, before and after the procedure. The goal was to see if the surgery changes this hormone level, which could help explain how the operation affects hunger and metabolism.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
36 people
The number who actually took part.
- Started
-
Jul 2025
- Finished
-
Nov 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Severe obesity patients scheduled for selective laparoscopic sleeve gastrectomy who have no associated medical problems
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18-65 years. * Patients with severe obesity (Body Mass Index (BMI) ≥ 40 kg/m²) with no additional comorbidities (Type III, Type IV, and Type V obesity) who are scheduled for primary LSG. * Patients who consent to participate in the study. Exclusion Criteria: * Patients who do not consent to participate in the study. * Patients scheduled for primary obesity surgery other than LSG (e.g., Single Anastomosis Gastric Bypass, Roux-en-Y Gastric Bypass, Transit Bipartition, Single Anastomosis Sleeve Ileal Bypass, Single Anastomosis Duodeno-intestinal Bypass, Duodenal Switch). * Patients with a BMI ≥ 35 kg/m² with associated medical problems (e.g., Diabetes Mellitus, Asthma, Chronic Obstructive Pulmonary Disease, Ischemic Heart Disease, Hypertension). * Patients with a BMI ≤ 35 kg/m² who do not have a surgical indication.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Obesity and overweight are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Elazığ Fethi Sekin City Hospital
Elâzığ, 23100, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can Weight-Loss surgery patients skip the opioids?
- Can tailoring bypass length improve weight loss surgery results?
- New injection IBI3046 tested for weight management
- Could cutting Ultra-Processed foods reverse childhood metabolic syndrome?
- Can big data reveal why some patients suffer after Weight-Loss surgery?
- Spinal cord stimulation: a surprising key to unlocking metabolism?