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Could a plant-based supplement help fight obesity? new trial tests polyphenols

NCT ID NCT07044167

Disease control Sponsor: Carmen Lucas Abellán Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested a polyphenol-enriched supplement in 70 overweight or obese adults to see if it could improve body weight, fat mass, and metabolic health. Participants took either the active supplement or a placebo for a period, and researchers measured changes in weight, insulin sensitivity, and inflammation. The goal is to find a natural way to support weight management.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Polyphenol-enriched dietary supplement
What this could lead to
If it works, this could point toward a natural supplement to help manage weight and improve metabolic health in people with overweight or obesity.
What could go wrong
This is a small, early-stage trial with only 70 participants. The supplement may show no meaningful benefit over placebo, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

70 people

The number who actually took part.

Started

Sep 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals of both sexes, aged 18 years or older. * Body Mass Index (BMI) between 25 and 35. * Clinical diagnosis of overweight or obesity according to established criteria. * Ability to understand and sign the informed consent form. Exclusion Criteria: * Presence of severe or terminal chronic diseases. * Current treatment with antioxidants or similar dietary supplements. * Known allergies to any of the product components. * Pregnancy or breastfeeding. * Participation in another clinical trial within the past 3 months.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obese subjects Obesity and overweight Overweight or obese Overweight or obese adults Overweight/obesity

Contacts and locations

Locations

  • UCAM San Antonio Catholic University of Murcia, Murcia, Murcia 30107

    Murcia, 30107, Spain

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