OVERWEIGHT , OBESITY

This study tests an investigational drug called MOTS-c in 120 adults with prediabetes and overweight or obesity. Participants receive either MOTS-c or a placebo for 12 weeks, along with lifestyle advice. The main goal is to see if MOTS-c improves how the body uses insulin, which …

This study looks at whether drinking a cranberry beverage can help overweight or obese adults improve their blood sugar, insulin levels, and cholesterol. Over 12 weeks, 73 participants will drink either cranberry or a placebo, then switch after a break. Researchers will also chec…

This study tests whether a special high-phenolic olive oil can improve metabolic health in 80 adults with central obesity (excess belly fat) and related issues like high blood pressure or cholesterol. Participants will consume either high-phenolic or low-phenolic olive oil daily …

This study tests whether asiaticoside, a compound from the herb Centella asiatica (Gotu Kola), can help adults with overweight or obesity lose weight. Researchers will measure changes in metabolic rate and body weight over 12 weeks. The study involves 30 participants and aims to …

This study looks at a community program that teaches families of children with overweight or obesity how to live healthier. About 160 children will be randomly assigned to either join the program right away or wait. The main goal is to see if the program helps improve the child's…

This study is testing whether using a smartwatch along with personalized digital health coaching can help people at risk for or with early-stage chronic conditions (like high blood pressure, prediabetes, or obesity) become more active and improve their health. About 1,700 adults …

This study tests whether using a smart wearable device (like a fitness tracker) along with health coaching can improve heart health in overweight or obese adults who have early warning signs like slightly high blood pressure, blood sugar, or cholesterol. About 1,400 participants …

This study looks at whether a single session of whole-body vibration can immediately improve blood pressure, heart rate, and walking ability in overweight or obese young women. 26 sedentary women aged 18-25 with a BMI between 25 and 40 will be recruited. The goal is to see if thi…

This study checks if a new multi-dose pen version of the BGM0504 injection works the same as the single-dose version in overweight or obese adults. About 144 people aged 18-55 with a BMI of 24 or higher will get one shot and have their blood levels measured. The goal is to see if…

This study looks at how different snacks (walnuts or pretzels) change brain activity related to food cravings and fullness during a 12-week weight-loss diet. Researchers will use brain scans to measure responses to food pictures. The goal is to understand which snack might help p…

This study is testing a 24-week program that combines nutrition counseling, exercise, sleep tips, and stress management for cancer survivors who are overweight. The goal is to see if the program is practical and helpful for improving sleep quality, reducing stress, and boosting i…

This early-phase study looks at how a single dose of ZT002 (a potential weight-loss drug) behaves in people with different levels of kidney function. About 40 adults who are overweight or obese will receive one injection, and researchers will measure drug levels and safety. The g…