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Kidney patients get first look at new obesity drug

NCT ID NCT07443059

First seen Mar 10, 2026 · Last updated Jun 20, 2026 · Updated 14 times

Summary

This early-stage study tests a single dose of Zovaglutide (ZT002), an experimental drug for overweight and obesity, in 40 adults with varying levels of kidney function. Researchers will measure how the drug moves through the body and check for side effects. The goal is to understand if kidney problems change how the drug works, not to treat kidney disease or cause weight loss.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sichuan Provincial People's Hospital

    RECRUITING

    Chengdu, Sichuan, 250014, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital Of Shandong First Medical Unversity

    RECRUITING

    Jinan, Shandong, 250014, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Xiamen University

    NOT_YET_RECRUITING

    Xiamen, Fujian, 361003, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Zovaglutide (ZT002 injection)

What this could lead to

If successful, this could help determine safe dosing of Zovaglutide for people with kidney problems who are overweight or obese.

What could go wrong

This is a very early Phase 1 study with only 40 participants. It focuses on drug levels and safety, not on weight loss or kidney improvement. Results may not apply to broader populations.

Conditions

The condition(s) this trial relates to.

chronic kidney disease Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.