10,000-Person obesity study aims to unlock personalized treatment secrets
NCT ID NCT07666425
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This observational study will follow 10,000 adults with obesity or overweight to understand how the disease progresses and what factors predict treatment success. Researchers will analyze medical records from 2000 onward, looking at heart and metabolic complications over 5 to 10 years. The goal is to identify patient subgroups and build models that help tailor future therapies.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better predict which obesity treatments work best for different patient groups, leading to more personalized care.
- What could go wrong
- This is an observational study, not a treatment trial. It collects existing data and does not test any new drug or intervention, so it cannot directly improve health outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 10,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Mar 2038
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will consist of adult patients meeting the study inclusion and exclusion criteria, with a current or past diagnosis of overweight or obesity defined in accordance with the most recent Italian clinical guidelines and the European framework promoted by the European Association for the Study of Obesity (EASO). Eligible patients will include individuals whose first access to the study site occurred on or after January 1, 2000.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Body mass index (BMI) ≥ 30 kg/m², or BMI ≥ 25 kg/m² with at least one cardiometabolic comorbidity * Provision of written informed consent Exclusion Criteria: * Obesity secondary to hypothalamic-pituitary disorders * Obesity secondary to adrenal disorders * Syndromic obesity
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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IRCCS Azienda Ospedaliero - Universitaria di Bologna
RECRUITINGBologna, Bologna, 40138, Italy
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