OVERWEIGHT , OBESITY

This study tests whether a smart lifestyle program that focuses on improving exercise capacity can help overweight or obese adults with metabolic syndrome. About 435 people aged 20 to 60 will either follow simple diet advice or a combined diet and exercise program. The goal is to…

This early-stage study tests a new drug called SRSD384 in 78 overweight or obese adults. The goal is to check its safety and how the body processes it, first alone and then with another weight loss drug. Participants must have a BMI between 27 and 40. This is not a cure but aims …

This study tests whether a 10-week camp program can reduce binge eating in 200 children aged 7-14. Some parents will also receive special training to see if it adds extra benefit. The goal is to help kids gain control over eating habits, not to cure the disorder, as ongoing manag…

This study tests a new drug called zovaglutide to help adults who are overweight or obese lose weight. About 744 participants will receive either the drug or a placebo for 52 weeks. The main goals are to see how much weight they lose and how many achieve at least a 5% weight loss…

This early-stage study tests a single dose of the experimental drug IBIO-600 in 32 overweight or obese adults. The main goal is to find a dose that is safe and well-tolerated, while also checking how the drug affects body composition. Participants must be in good general health w…

This study tests whether a daily probiotic called AKM Lab-01 can help overweight or obese adults lose weight safely. About 200 participants will take either the probiotic or a placebo for 3 months. Researchers will measure changes in body weight, BMI, blood sugar, and gut bacteri…

This study tests whether adding metformin (a diabetes drug) to secukinumab (a standard psoriasis medication) works better than secukinumab alone for controlling moderate-to-severe plaque psoriasis in overweight or obese Chinese adults. About 186 participants will receive either t…

This study tests a community-based exercise program for adults aged 50 and older who have at least two chronic conditions, such as heart disease, diabetes, or arthritis. The goal is to see if personalized exercise can improve heart and muscle fitness, mobility, and overall well-b…

This study tests if a family-based weight management program can slow the start of puberty in girls aged 6.5 to 8 who are overweight or obese. Half the girls will join a 5-month program focused on healthy eating and exercise, while the other half will receive usual care. Research…

This study tests a new physical education program designed to prevent common health issues like myopia, overweight, and anxiety in 200 junior high students. The program combines exercise with health education, aiming to address multiple conditions at once. Researchers will compar…

This early-stage study looks at how an experimental long-acting drug called ZT002 affects the way the body processes four common medicines (metformin, warfarin, rosuvastatin, and digoxin) in overweight and obese adults aged 18 to 45. About 60 healthy volunteers will take these me…

This study looks at how eating mostly ultra-processed foods versus less-processed foods affects heart health markers like blood pressure and cholesterol. About 79 overweight adults will follow special diets to see the differences. The goal is to understand how food processing imp…

This study looks at whether exercising in the morning or evening helps people with prediabetes control their blood sugar better. Researchers will study 28 adults who are overweight and have an extreme natural body clock. Each person will try no exercise, morning exercise, and eve…

This study looks at how exercise changes the way the brain responds to stress and food in overweight veterans. Researchers will use brain scans and hormone tests to understand these effects. The goal is to learn more about why some people eat more when stressed and how exercise m…

This study looks at how well tirzepatide, a newer weight-loss medication, works when used in regular doctor visits—not just in strict research settings. Researchers will track weight loss and dosing patterns in 1700 adults with obesity across multiple Dutch clinics over six month…

This study looks at whether one session of a non-invasive brain stimulation technique called rTMS can change how the heart and brain communicate in women who have had multiple pregnancy losses and are overweight or obese. Sixty women will be randomly assigned to receive either re…