Tailored exercise may boost fat burning in women with PCOS
NCT ID NCT07659392
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study investigates whether a supervised, adapted physical activity program can improve how the body burns fat during walking in women with overweight or obesity, both with and without polycystic ovary syndrome (PCOS). Researchers will compare changes in fat oxidation and other health measures—like blood pressure, body composition, and fitness—between the two groups. The goal is to understand how PCOS affects metabolism and whether targeted exercise can help manage cardiometabolic risks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- adapted physical activity program
- What this could lead to
- If successful, this could point toward exercise-based strategies to improve cardiometabolic health in women with PCOS and obesity.
- What could go wrong
- This is a small, early-stage study with only 40 participants, so results may not apply to all women. The intervention is behavioral, and adherence or long-term effects are uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Women aged 18 to 40 years (inclusive boundaries) * Women with a body mass index (BMI) between 25 and 40 kg/m² * Women performing no more than 150 minutes of moderate-to-vigorous physical activity per week * Women able to provide informed consent to participate * Women affiliated with a social security system * One group will consist of women with polycystic ovary syndrome, and another group will consist of women without polycystic ovary syndrome Exclusion Criteria: * Pregnancy or breastfeeding, as declared by the participant * Postmenopausal women * Women currently receiving pharmacological treatment for obesity or who have received such treatment within the past two years * Women under legal protection measures (guardianship, curatorship, or judicial protection) * Refusal to sign the informed consent form
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU de Clermont-Ferrand
Clermont-Ferrand, 63000, France
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