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Can antioxidant pills boost skin and blood carotenoids to improve cardiometabolic health?

NCT ID NCT07748468

Disease control Sponsor: National University of Singapore Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This trial tests whether taking antioxidant-rich supplements for 12 weeks can improve skin and blood carotenoid levels, antioxidant status, and cardiometabolic health in overweight and obese adults aged 21-70. Participants maintain their usual diet while adding either LifePak Element or LifePak Optimal daily. The study measures changes in skin carotenoid scores, blood carotenoid concentrations, and total antioxidant capacity to see if these supplements offer measurable benefits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Antioxidant-rich dietary supplements (LifePak Element and LifePak Optimal)
What this could lead to
If effective, these supplements could support better antioxidant status and cardiometabolic health in overweight and obese individuals, potentially informing dietary recommendations.
What could go wrong
This is an early-stage trial with a modest sample size, and results may not translate to broader populations. Supplements may have limited impact on cardiometabolic outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 83 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Able to give informed consent (AMT score ≥ 8 for older adults \[65-70 years old\]) * Adults 21-70 years old * English-literate * Have venous access sufficient to allow for blood sampling as per the protocol * No drastic change of diet for the past 1 year * If taking medication, has been consistently taking antihypertensive/cholesterol-lowering/type-2 diabetic medication for more than 3 years prior to starting the study Exclusion Criteria: * Weight change \> 3kg in the past 3 months * Exercising vigorously over the past 3 months * Taking medications or dietary supplements which may impact eye/skin health * Taking lipid-lowering and blood pressure controlling medications less than 3 years * Smoking * Drinking more than 2 alcoholic drinks per day * Pregnant, lactating, or planning pregnancy in the next 6 months

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Antioxidant status Overweight/obesity

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • NUS, Department of Food Science and Technology, 1 Science Drive 3, Block S13, #03-07, Singapore, 117550

    Singapore, 117542, Singapore

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