New Weight-Loss injection under study: will it work the same?
NCT ID NCT07382908
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two versions of an experimental injection called BGM0504 to see if they work the same way in the body. It involves 144 overweight or obese adults aged 18-55. Participants receive a single dose, and researchers measure drug levels and monitor for side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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About 144 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Feb 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 55 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18-55 years (inclusive). * Male weight ≥50 kg, female weight ≥45 kg, and overweight (24.0 ≤ BMI \< 28.0 kg/m²) or obese (BMI ≥ 28.0 kg/m²). * From signing the ICF until 3 months after dosing, no pregnancy plan and willing to use effective contraception to avoid pregnancy or causing partner pregnancy, and no plan for sperm/egg donation. * The participant fully understands the trial purpose, nature, methods, and potential adverse reactions, can complete the trial according to the protocol, has good living habits, can maintain good communication with the investigator, and voluntarily signs the ICF. Exclusion Criteria: * History of severe allergies or severe specific allergic diseases/history (asthma, urticaria, eczematous dermatitis, etc.) or allergic constitution (allergic to two or more foods or drugs), known or suspected allergy to any excipient of BGM0504 Injection. * Previous diagnosis of type 1 or type 2 diabetes, or clinically significant abnormal HbA1c at screening. * Family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 syndrome. * History of acute/chronic pancreatitis, pancreatic injury, or other high-risk factors for pancreatitis. * Past or screening findings of digestive system diseases that may increase participant risk. * Positive for HBsAg, HCV antibody, syphilis antibody, or HIV antibody at screening. * Participation in any drug or medical device clinical trial and receiving investigational product/device intervention within 3 months prior to screening. * Consumption or plan to consume specific foods (including pitaya, mango, grapefruit, pomelo or their juices, high-purine foods like animal organs, seafood, chocolate) or beverages containing caffeine/alcohol within 48 hours before dosing; or unwilling to stop consuming these during the in-house period. * Pregnant or breastfeeding women, or positive pregnancy test at screening. * Any other condition considered by the investigator as unsuitable for participation or participant withdrawal due to personal reasons..
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hangzhou First People's Hospital
RECRUITINGHangzhou, Zhejiang, 310006, China
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