Obesity and overweight

Researchers are testing an experimental injectable drug called IBI3046 in Chinese adults who are overweight or obese. The trial checks the drug's safety, how the body processes it, and how it affects body weight. Participants receive IBI3046 alone, in combination with another dru…

This trial compares two approaches to weight loss: a traditional energy-restricted diet versus a personalized dietary plan tailored to each person's metabolism, body composition, eating habits, and preferences. About 800 adults with obesity (BMI 28 or higher) will be followed for…

This phase 2 trial tests whether quercetin, a dietary supplement found in many fruits and vegetables, can improve the function of tiny blood vessels in young adults with obesity. Forty participants will take either quercetin or a placebo daily for 30 days. Researchers will measur…

This phase 2 study tests an experimental oral drug, NA-931, alone or with an approved injectable weight-loss medication (tirzepatide), in 224 overweight or obese adults aged 18-80. The main goal is to see how much weight participants lose over 48 weeks compared to placebo. The st…

This study looks at whether using ultrasound to measure neck tissue thickness can better predict difficult airway in obese patients undergoing surgery. Researchers will compare ultrasound measurements with standard tests in 52 adults. The goal is to improve safety during anesthes…

This study looks at whether eating chia seeds while breastfeeding can change the makeup of breast milk and reduce inflammation in mothers who are overweight. About 80 mothers will take chia seeds for 6 weeks, and researchers will measure nutrients and health markers in their milk…

This study works with 35 primary care clinics to help them screen patients for physical inactivity and refer them to community-based exercise programs. The goal is to see if this approach can be smoothly integrated into routine care and whether it leads to better health outcomes …

This study looks at how the body's energy use changes when overweight or obese adolescents walk with simulated weight loss. Researchers will use a special treadmill that reduces the effect of gravity to mimic being at a normal or overweight weight. By measuring energy burned and …