NICOTINE DEPENDENCE

This small pilot study looked at whether giving free e-cigarettes to smokers who hadn't quit after lung cancer screening could help them smoke fewer regular cigarettes. Fifteen people who still smoked were offered e-cigarettes for 4 weeks and then followed for another 4 weeks. Th…

This study tested whether topiramate, a seizure medication, can help people who are dependent on both alcohol and nicotine. 236 adults who drank heavily and smoked at least 5 cigarettes daily took either a high or low dose of topiramate or a placebo for 18 weeks. The goal was to …

This study looked at whether switching from regular cigarettes to either low or high wattage e-cigarettes helps people smoke less or quit. 372 adult smokers who weren't planning to quit joined the study. Researchers measured how many people stopped smoking and checked their breat…

This study tested whether using lemongrass inhalers or liquid vapor could help adult smokers reduce their nicotine dependence and improve related health markers. Two hundred smokers aged 18-30 took part, using lemongrass products or no intervention. Researchers measured changes i…

This study tested a 9-session program that uses cognitive-behavioral techniques to help people living with HIV quit smoking by reducing anxiety and depression. 131 daily smokers who were motivated to quit took part. The goal was to see if the program led to higher quit rates comp…

This study looked at how nicotine addiction changes brain activity and which genes might make quitting harder. Researchers used brain scans and genetic tests on 159 current and former smokers, as well as non-smokers. The goal was to find biological markers that could predict who …

This study tested two types of brain stimulation (TMS) in 90 nicotine users, some with schizophrenia and some without. The goal was to see if the stimulation could change brain connections and reduce cravings for nicotine. Participants completed tasks and reported their cravings …

This study looked at how nicotine salt-based vaping products deliver nicotine into the blood compared to regular free-base nicotine e-liquids. Fifteen daily vapers took part, and researchers measured nicotine levels, harshness, and satisfaction. The goal was to understand the abu…

This study looked at how nicotine from a standardized research e-cigarette (SREC) compares to nicotine from a person's usual e-cigarette brand. 32 regular e-cigarette users took part. Researchers measured nicotine levels in the blood, puffing patterns, and how people felt after v…

This study tested new computer tasks to see how drugs affect brain activity using MRI scans. Healthy volunteers aged 18 to 65, both drug users and non-users, performed memory and reaction-time tests while in a scanner. The goal was to develop reliable tools for future research on…