Can aerobic exercise at the YMCA help Stress-Sensitive smokers kick the habit?
NCT ID NCT03080090
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a 15-week aerobic exercise program at the YMCA can help smokers who are highly sensitive to stress quit smoking. Participants work with a personal trainer three times a week and also receive support from a national quitline. The goal is to see if exercise reduces stress sensitivity and improves long-term quit rates.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- aerobic exercise
- What this could lead to
- If it works, this could offer a community-based, drug-free way to help stress-sensitive smokers quit successfully.
- What could go wrong
- This is an early-stage trial with 150 participants, so results may not apply to all smokers. Exercise may not be enough to overcome nicotine addiction for everyone.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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150 people
The number who actually took part.
- Started
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Apr 2017
- Finished
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Jul 2020
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male and female participants ages 18-65 * Willing and able to provide informed consent, attend all study visits and comply with the protocol * Daily smoker for at least one year * Currently smoke an average of at least 5 cigarettes per day * Report a motivation to quit smoking in the next month of at least 5 on a 10-point scale. * Anxiety Sensitivity Index-3 score ≥ 23 (cut-off score to identify high AS individuals) * Sedentary as defined by moderate-intensity exercise less than 3 days/wk for at least 20 minutes each time * Medical clearance to participate in the protocol Exclusion Criteria: * Use of other tobacco products (including e-cigarettes) * A lifetime history of bipolar disorder, schizophrenia, psychosis, or delusional disorders; an eating disorder in the past 6 months; organic brain syndrome, mental retardation or other cognitive dysfunction that could interfere with capacity to engage in therapy; a history of substance or alcohol abuse or dependence (other than nicotine) in the last 6 months or otherwise unable to commit to refraining from alcohol use during the acute period of study participation. * Patients with significant suicidal ideation as determined by structured interview or who have enacted suicidal behaviors within 6 months prior to intake will be excluded from study participation and referred for appropriate clinical intervention. * Body mass index 40. We selected a BMI of 39.9 as the upper limit in order to screen out individuals with Class III obesity who might be more prone to musculoskeletal injuries than individuals with a BMI\<40.0). * Current use of any psychotherapy for smoking cessation not provided by the researchers. * Current use of any pharmacotherapy or psychotherapy for smoking cessation not provided by the researchers during the quit attempt, including Chantix, Zyban, and Nicotine Replacement Treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Texas at Austin
Austin, Texas, 78712, United States
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