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Scientists use brain scans and phones to decode addiction

NCT ID NCT02334956

Knowledge-focused Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study combined brain imaging with real-world data from mobile devices to explore how addiction affects the brain. Researchers scanned the brains of 107 people with alcohol, cannabis, or nicotine dependence, along with healthy controls. They also tracked cravings and daily functioning using mobile technology. The goal was to better understand the brain processes behind addiction, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help researchers better understand how addiction works in the brain, potentially pointing toward new ways to predict or manage cravings.
What could go wrong
This is an observational study, not a treatment trial. It is small and early-stage, so findings may not apply to everyone or lead directly to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

107 people

The number who actually took part.

Started

Mar 2015

Finished

Jan 2018

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 64 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion criteria patient: * Aged 18-64 years * Being affiliated to health insurance * Having signed an informed consent (later than the day of inclusion and before any examination required by research) * Participation in the study MOBICOG for patients with addiction * Fulfils diagnostic criteria for one of the following groups: Group A: Patients with current (last 12 months) Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) substance addiction (Alcohol / Cannabis / Nicotine); initiation of treatment for addiction within 30 days preceding enrollment in the study; absence of other axis 1 psychiatric disorder currently being treated (by psychotherapy or pharmacotherapy); absence of current or lifetime bipolar disorder or schizophrenia. Group AM: Patients with current (last 12 months) DSM-IV substance addiction (Alcohol / Cannabis / Nicotine); initiation of treatment for addiction within 30 days preceding enrollment in the study; presence of currently treated unipolar mood disorder (by psychotherapy or pharmacotherapy); absence of current or lifetime bipolar disorder or schizophrenia. Group AS: Patients currently treated for DSM-IV schizophrenia (last 12 months) with DSM-IV substance addiction (Alcohol / Cannabis / Nicotine); absence of other axis 1 psychiatric disorder currently being treated (by psychotherapy or pharmacotherapy); absence of current or lifetime bipolar disorder. Inclusion criteria healthy volunteers: * Aged 18-64 years * Participation in the study MOBICOG * Being affiliated to health insurance * Having signed an informed consent (later than the day of inclusion and before any examination required by research) * Healthy volunteers without current addiction and with no other currently-treated axis 1 DSM-IV disorder (by psychotherapy or pharmacotherapy); absence of current or lifetime bipolar disorder or schizophrenia Exclusion Criteria: * Presence of a counter-indication for MRI * Presence of any health problem preventing travel to the imaging service of the University Hospital * Being unable to provide consent to participate * Pregnant or breastfeeding woman

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Conditions

The condition(s) this trial relates to.

alcohol dependence Behavior, Addictive cannabis dependence nicotine dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Addiction

Contacts and locations

Locations

  • CHU de Bordeaux

    Bordeaux, 33000, France

  • Hôpital Charles Perrens

    Bordeaux, 33076, France

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