NEPHROLITHIASIS
Clinical trials for NEPHROLITHIASIS explained in plain language.
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New study compares two keyhole surgeries for kidney stones
Disease control CompletedThis study looked at 60 adults with kidney stones between 2 and 3 cm. It compared two types of keyhole surgery: one using a flexible scope through the urine passage with a laser and suction, and the other using a tiny cut in the back. The goal was to see which method removes ston…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Necmettin Erbakan University • Aim: Disease control
Last updated May 26, 2026 07:24 UTC
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New study finds best method for small kidney stone removal
Disease control CompletedThis study looked at three different methods for removing kidney stones up to 2 centimeters in size. 90 adults with a single kidney stone were randomly assigned to one of three groups: surgery with a traditional tube, surgery with a suction tube, or surgery without any tube. The …
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated May 26, 2026 07:24 UTC
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Sound waves shatter kidney stones without surgery
Disease control CompletedThis study tested a device called Break Wave™ that uses sound waves to break kidney stones into tiny pieces. 64 adults with stones in the upper urinary tract took part. The goal was to see if the device is safe and can break stones into fragments small enough to pass on their own…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: SonoMotion • Aim: Disease control
Last updated May 20, 2026 11:56 UTC
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New study finds best way to zap kidney stones in kids
Disease control CompletedThis study looked at 180 children aged 6 to 12 with hard kidney stones (1-2 cm) in the lower part of the kidney. It compared two surgeries: mini percutaneous nephrolithotomy (a small tube through the back) and flexible ureteroscopy (a scope through the urinary tract). The goal wa…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New study tests best strategy to stop kidney stones
Disease control CompletedThis study tested two approaches to prevent kidney stones in adults who have had at least two stones in the past five years. One group received a personalized prevention plan based on their urine test results, while the other group followed a standard diet and medication plan. Th…
Matched conditions: NEPHROLITHIASIS
Phase: PHASE4 • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated May 11, 2026 20:48 UTC
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New laser microscope may replace biopsies for urinary tract cancer detection
Diagnosis CompletedThis study tested whether a special laser microscope, used during a scope procedure of the kidney and ureter, can accurately tell normal tissue from tumors in the upper urinary tract. 29 adults with blood in urine, kidney stones, or other urinary issues took part. The goal was to…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Lille Catholic University • Aim: Diagnosis
Last updated May 26, 2026 07:50 UTC
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New suction tool may improve kidney stone removal
Symptom relief CompletedThis study tested two different tools used during surgery to remove kidney stones up to 20 mm. One is a traditional sheath that lets fluid and stone fragments flow out passively, and the other is a newer suction sheath that actively pulls out fragments. The goal was to see which …
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated May 26, 2026 07:53 UTC
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No-Tube kidney stone surgery may mean less pain for kids
Symptom relief CompletedThis study looked at 640 children aged 6 to 18 who needed surgery for large kidney stones. Half got the standard surgery with a temporary drainage tube left in the kidney, and half got a newer 'tubeless' version without the tube. The goal was to see if the tubeless method is just…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Lady Reading Hospital, Pakistan • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC
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Pills before surgery may help remove kidney stones faster
Symptom relief CompletedThis study tested whether taking tadalafil (Cialis), tamsulosin (Flomax), or both before kidney stone surgery helps doctors place a larger tube (access sheath) to remove stones more easily. 220 adults having surgery for kidney stones were randomly assigned to one of four groups: …
Matched conditions: NEPHROLITHIASIS
Phase: PHASE4 • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated May 20, 2026 11:53 UTC
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New suction tool may speed up kidney stone surgery
Symptom relief CompletedThis study tested whether a new flexible access sheath with suction can make kidney stone surgery faster and safer compared to a standard sheath. Fifty adults with kidney stones 10 mm or larger were randomly assigned to one of the two sheaths during a minimally invasive procedure…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Barzilai Medical Center • Aim: Symptom relief
Last updated May 18, 2026 12:10 UTC
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Nerve block eases pain after kidney stone procedure
Symptom relief CompletedThis study tested whether a special nerve block called the erector spinae plane (ESP) block can improve pain relief after flexible ureteroscopy (URS) surgery for kidney stones. Seventy adults were randomly assigned to receive either the ESP block plus standard pain care or standa…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Namik Kemal University • Aim: Symptom relief
Last updated May 18, 2026 12:06 UTC
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Which anesthesia is safer for your eyes during kidney stone surgery?
Knowledge-focused CompletedThis study looked at 60 adults having kidney stone surgery to see how different anesthesia flows affect eye pressure and the optic nerve. Patients were placed face-down and given either low-flow or high-flow anesthesia. The goal was to find which method better protects the eyes d…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Elazıg Fethi Sekin Sehir Hastanesi • Aim: Knowledge-focused
Last updated May 26, 2026 07:51 UTC
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Can a smart water bottle stop kidney stones? new study says maybe
Knowledge-focused CompletedThis study looked at why and how people with a history of kidney stones stick to drinking more fluids. Researchers gave 172 adults a smart water bottle and a phone app to track their water intake for 3 months. The goal was to understand what helps people form healthy habits, not …
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated May 26, 2026 07:25 UTC
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Which anesthesia causes less inflammation during kidney stone surgery?
Knowledge-focused CompletedThis study looked at 90 adults having kidney stone surgery to see if spinal or general anesthesia affects inflammation differently. Researchers used routine blood tests (NLR, RDW, LAR) taken before and after surgery. No extra blood draws were needed. The goal was to learn which a…
Matched conditions: NEPHROLITHIASIS
Sponsor: Sevim Şenol Karataş • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC