NEPHROLITHIASIS

This study compares two new suction-equipped tools (FANS and CVAC) for removing medium-to-large kidney stones. About 159 adults with stones 8-20 mm will be randomly assigned to one device. The main goal is to see which tool leaves the kidney more stone-free, as confirmed by CT sc…

This study looks at whether sodium bicarbonate, a low-cost medicine, can work as well as potassium citrate to prevent kidney stones. About 30 adults with a history of kidney stones and low citrate levels will take sodium bicarbonate for a short time. Researchers will measure chan…

This study tests whether rinsing the kidney with a special solution (dioxidine) after stone-removal surgery can stop new infection-related kidney stones from coming back. About 95 adults who have surgery for infection stones will either get standard care or standard care plus the…

This study compares two suction-assisted techniques used during minimally invasive kidney stone surgery. The goal is to see which method better removes stone fragments and lowers the risk of infection. About 126 adults with medium-sized kidney stones (2-3 cm) will be randomly ass…

This study looks at whether a specific nerve block, called an erector spinae plane block, can help reduce pain and the need for strong painkillers after kidney stone removal surgery. About 60 adults having this surgery will either get the nerve block plus standard care or standar…

This study looks at whether having just one altered copy of the CYP24A1 gene (instead of two) makes people more likely to develop kidney stones. Researchers will compare 45 people with one or two altered gene copies to understand their health and lab results. The goal is to clari…

This study watches how different pain relief methods work for people after kidney stone surgery. Doctors choose the pain treatment as usual, and the study just records what happens. The goal is to find which method works best with the least side effects. About 75 adults will take…