MILD COGNITIVE IMPAIRMENT

This study tests two computer-based brain training programs in 84 older adults (65+) with mild cognitive impairment. The goal is to see if these exercises can improve brain function and memory. Participants will use the programs at home and have brain scans to measure changes.

This study tests a 6-week program for older adults (55+) who have both diabetes and mild memory or thinking problems. Participants attend weekly group sessions with their caregiver to learn better diabetes self-care. The goal is to see if the program improves blood sugar control …

This small pilot study will test whether adding one infusion of human mesenchymal stem cells to standard antibody therapy can help stabilize memory and daily function in people with mild Alzheimer's or mild cognitive impairment. Ten participants aged 55-90 who have been on antibo…

This study tests a special sleep therapy called SleepSMART for veterans who have both insomnia and mild cognitive impairment (MCI). The therapy adapts standard insomnia treatment with extra memory and learning support. Researchers will compare SleepSMART to standard therapy in 15…

This study looks at whether a carefully planned ketogenic diet can help people who have both osteoarthritis (joint pain) and mild cognitive impairment (memory issues). Ten adults will follow the diet under supervision for a period, and researchers will measure changes in pain, ph…

This study tests whether a 5-week virtual cognitive training program works as well as an 8-week version for people aged 65+ with mild cognitive impairment (MCI). Participants will attend weekly group sessions online and complete memory tests and questionnaires. The goal is to imp…

This pilot study tests whether a non-invasive technique called transcranial alternating current stimulation (tACS) can improve working memory in 30 adults with mild cognitive impairment or traumatic brain injury. Participants will receive gentle electrical stimulation to the brai…

This study tests whether group body percussion training—clapping, tapping, and snapping to a beat—can improve movement, attention, and daily function in 25 adolescents aged 14-18 with mild intellectual disability. Participants will either take part in 8 weeks of structured rhythm…

This study looks at whether the seizure drug brivaracetam can calm overactive brain activity in people with mild Alzheimer's or mild cognitive impairment. Researchers will place tiny electrodes in the brain to measure abnormal electrical signals. The goal is to see if reducing th…

This study tests whether daily exposure to a blend of essential oils can improve mood and behavior in people with mild cognitive impairment or early dementia, and also reduce stress for their caregivers. About 200 patients and their caregivers will try aromatherapy at home for at…

This study tests whether a 6-week program of therapeutic video games (exergames) can improve movement, balance, and quality of life in older adults with mild cognitive impairment living in long-term care. About 38 participants will either play exergames or do standard physiothera…

This study tests whether combining a non-invasive brain stimulation technique (rTMS) with walking and eye-movement exercises can improve balance and walking in people with mild cognitive impairment. Researchers will enroll 30 adults aged 18-80 to see if the approach is feasible a…

This study is creating and testing a computer program that adapts to the needs of older adults with mild cognitive impairment (MCI). The program aims to provide mental and social support, and may also detect early signs of worsening memory by analyzing speech. About 290 people ag…

This study aims to develop and test digital assistant tools to help older adults, including those with mild cognitive impairment, manage healthcare tasks like finding services, handling medical bills, and using Medicare.gov. Researchers will interview 600 participants to understa…

This study looks at whether Ginkgo biloba, a common herbal supplement, can affect certain blood markers linked to Alzheimer's disease. Researchers will give either Ginkgo biloba or a placebo to 120 adults with mild memory problems for 6 months. They will measure changes in blood …

This study will follow 1,000 older adults (age 50+) from under-resourced communities who have early memory concerns. Researchers will collect health data, brain scans, and samples over time to learn how memory problems progress. The goal is to better understand dementia risk in g…

This study follows 285 older adults (65+) with Alzheimer's or mild cognitive impairment, along with their caregivers, to understand how they make decisions about staying at home or moving to long-term care. Researchers will track planning over time, looking at factors like thinki…

This study will follow 2,500 elderly people in Hong Kong for 2-3 years to find better ways to detect Alzheimer's disease early. Researchers will use blood tests and brain scans to see who might develop memory problems. The goal is to create a Chinese-specific resource to help pro…

This study tests if a non-invasive brain stimulation technique called TMS can help the brain's natural waste-clearing system remove proteins linked to Alzheimer's disease. Researchers will study 20 older adults with mild cognitive impairment to see if TMS improves thinking and re…

This study will see if wearable devices like smartwatches and rings can catch early signs of memory loss and Alzheimer's disease. Researchers will track 150 adults aged 65 and older, comparing data from wearables with brain scans, blood tests, and thinking tests. The goal is to f…

This study will test a virtual reality (VR) program called CAST, designed for older adults with mild cognitive impairment. The goal is to see if the program is easy to use, enjoyable, and helpful for staying socially connected. Researchers will track how often participants use th…