LUNG CANCER (DIAGNOSIS)

This study looks at whether finding and treating COPD early can help people who are also being checked for lung cancer. About 280 adults with breathing problems will get either standard care or extra COPD treatment. The goal is to see if this improves symptoms, quality of life, a…

This study tests a new treatment called EBNK-001, which uses donor immune cells (natural killer cells) to fight advanced solid tumors. About 83 adults with cancers like lung, breast, or colorectal cancer that have not responded to standard treatments will receive these cells alon…

This study is testing a device called Inflammacheck that measures certain chemicals in a person's breath to see if it can help tell if someone has lung cancer. The goal is to create a simple, non-invasive tool that could be used in clinics to quickly decide who needs further test…

This study is testing a new blood test that measures telomeres (parts of your DNA) to help doctors figure out if someone has lung cancer. Researchers will compare results from 1200 people—some with lung cancer and some without—to build a model that predicts cancer risk. The goal …

This study is testing whether a blood test, combined with artificial intelligence (AI), can help find lung cancer early in people with COPD who are current or former smokers. About 1,000 participants will give a blood sample, and the AI will analyze it to see who has a higher ris…

This study looks at whether a blood test that analyzes DNA fragments (cfDNA fragmentomics) can accurately tell if lung nodules found on CT scans are benign or malignant. Researchers will enroll 240 adults with small to medium-sized lung nodules. If successful, this noninvasive ap…

This study compares three different ways of taking a lung tissue sample (needle biopsy) in people suspected of having lung cancer. The goal is to see which method provides the best quality sample for accurate diagnosis. About 54 adults with tumors near the chest wall will take pa…

This study tests whether combining a referral to a lung cancer screening program with text message reminders can increase screening rates among emergency department patients. About 300 eligible smokers aged 50-80 will be randomly assigned to receive either a basic referral or a f…

This study tests a new way to create detailed 3D images of lung and colorectal cancer tissue. Researchers will use a special preprocessing system and staining technique to get clearer pictures than standard 2D methods. The goal is to help doctors diagnose cancer more accurately a…

This study looks at whether doctors need to change the needle between sampling different lymph nodes during a lung cancer staging procedure called EBUS-TBNA. About 30 people with suspected or confirmed lung cancer will have two rounds of staging: one with a fresh needle for each …

This study is testing a new test called FlowPath Lung that looks for lung cancer cells in sputum (phlegm). It is for people aged 50-80 who are at high risk for lung cancer and have a lung nodule between 6 and 30 mm. The goal is to see if this test can accurately detect early-stag…

This study tests if acupressure can reduce coughing and related symptoms like shortness of breath and fatigue in lung cancer survivors. 80 participants will either receive acupressure for 8 weeks or get an education booklet. The goal is to see if this simple, non-drug technique i…

This study looks at whether yoga and mindfulness can improve the emotional, social, and physical well-being of people who have survived lung, colon, or non-Hodgkin's lymphoma cancer. Researchers will also check if these practices affect inflammation and gene activity. About 100 a…

This study tests whether a supplement made from the Antrodia cinnamomea mushroom can improve quality of life for people with lung cancer who are receiving platinum-based chemotherapy. About 40 participants will take either the supplement or a placebo for 3 months. Researchers wil…

This study looks at two different ways to reach out to lung cancer patients who may need help with anxiety or depression. The goal is to see which method works better at getting patients to start a telehealth program that offers counseling and support. About 30 adults being treat…

This study aims to understand how lung cancer changes when it spreads to other parts of the body. Researchers will compare DNA from the original tumor and the metastatic site in 25 adults with non-small cell lung cancer. The goal is to learn more about cancer progression, not to …

This study looks at whether a smartphone app can encourage mothers of children aged 4 and under to test their homes for radon, a gas that is the second leading cause of lung cancer. About 100 mothers will get a free radon test kit and complete surveys to see if the app boosts the…

This study is observing how lung cancer patients respond to the drug Tislelizumab in real-world clinics, not a controlled lab setting. Researchers will track survival, side effects, and quality of life in 240 participants across Germany and Austria. The goal is to understand how …

This study watches 300 lung cancer patients to see how they recover after one of two common surgeries: removing a small part of the lung (sublobar resection) or a larger section (lobectomy). Patients wear a digital device and answer questions about pain, cough, tiredness, and oth…

This study follows 900 lung cancer surgery patients for 30 days after their operation. Researchers collect medical data to find which factors increase the risk of developing blood clots in the legs (deep vein thrombosis). They will use machine learning to create a tool that predi…

This study looks at whether giving extra oxygen to the lung that is not being used during lung cancer surgery can lower inflammation and improve recovery. About 56 adults having lung cancer surgery will take part. Researchers will measure markers of oxygen levels and inflammation…

This study looks at how well a virtual oncology program works for veterans newly diagnosed with lung, colorectal, prostate, or breast cancer. Researchers will track telehealth visits, quality of care, and costs over 36 months. The goal is to see if this program helps veterans get…

This study tests a community-based program to help underserved adults get screened for lung, breast, and prostate cancers. About 200 people who meet screening guidelines will be offered navigation support at community resource spots. The goal is to see if this approach increases …

This study is observing whether a pain-blocking injection given during chest surgery can lower the chance of serious problems like lung infections or breathing trouble afterward. About 500 adults having keyhole or robot-assisted chest surgery will take part. The goal is to see if…

This study looks at how immune cells behave in lung cancer, COPD, and sarcoidosis. Researchers want to understand why some people don't respond to immunotherapy. The goal is to gather knowledge that could lead to more personalized treatments in the future. About 425 participants,…