AI blood test could catch lung cancer early in smokers with COPD
NCT ID NCT07552584
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether a simple blood test, combined with artificial intelligence (AI), can help find lung cancer early in people with COPD who are current or former smokers. About 1,000 participants will give a blood sample, and those flagged as high-risk by the AI will get a low-dose CT scan. The goal is to see if this approach is practical and safe for use in primary care, potentially catching cancer sooner and reducing unnecessary scans.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Apr 2034
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed with COPD. * =\> 50 years. * Former or current smoker. * Speaks and understands Danish. * Able to give informed consent to participation. Exclusion Criteria: * Had a CT scan of the thorax within 6 months. * Received active treatment for cancer within one year (except non-melanoma skin cancer and carcinoma in situ cervicis uteri). * Diagnosed with cancer within one year (except non-melanoma skin cancer and carcinoma in situ cervicis uteri). * Presents with symptoms giving suspicion of cancer (except non-melanoma skin cancer and carcinoma in situ cervicis uteri). * In a condition not allowing diagnostic workup for or treatment of lung cancer. * Does not have Eboks (electronic communication with Danish authorities).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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General practices, Vejle area
RECRUITINGVejle, Denmark
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Lillebaelt Hospital Vejle, University Hospital of Southern Denmark
RECRUITINGVejle, 7100, Denmark
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