Knee arthritis, osteoarthritis

This study tests whether wearing a knee sleeve daily for five years can slow the progression of knee arthritis and reduce pain in adults aged 50 to 64 who have had knee pain for at least three months. Participants are randomly assigned to either wear a knee sleeve every day or no…

This trial tests whether adding motivational interviewing—a counseling style that strengthens personal motivation—to a standard exercise program helps people with knee osteoarthritis feel more confident about exercising and managing pain. About 56 participants will be randomly as…

This study tests a single injection of StromaForte, made from donor bone marrow cells, against a standard hyaluronic acid injection for knee osteoarthritis. About 140 adults with knee arthritis will receive one treatment and be followed for 12 months. The main goal is to see if S…

This study will compare the effects of a single injection of platelet-rich plasma (PRP) versus conditioned serum (CS) in 60 people with knee osteoarthritis. Participants must have had knee pain for at least 6 months and meet specific criteria. The goal is to see which treatment b…

This trial tests whether adding a structured patient education program to standard physical therapy helps people with chronic low back pain, knee osteoarthritis, or shoulder pain stick to their prescribed home exercises. Participants will be randomly assigned to receive either st…

This trial tests whether eccentric strengthening exercises or low-load blood flow restriction training can improve muscle function, strength, and daily mobility in people with knee osteoarthritis. Participants aged 40 to 70 with mild to moderate knee arthritis will follow a four-…

This trial tests whether pressure biofeedback training—using a device that shows how hard you press—can reduce pain and improve muscle function better than bolster foam rolling in people with knee osteoarthritis. Forty-eight participants with moderate knee arthritis will do one o…

This study compares two types of balance and strength exercises added to standard physical therapy for knee osteoarthritis. Sixty adults aged 40-70 with mild to moderate knee arthritis will be randomly assigned to one of two exercise programs. The goal is to see which approach be…

This study tests whether adding special balance platform exercises to standard physical therapy can improve pain, balance, and daily function in people with knee osteoarthritis. About 36 adults aged 45-65 with moderate knee arthritis will be randomly assigned to either standard t…

This study tests whether high-intensity laser therapy (HILT) plus exercise works better than standard physical therapy plus exercise for knee osteoarthritis. One hundred adults aged 40 to 75 with knee arthritis will be split into two groups to compare pain relief, joint function,…

This study tests if freezing the nerves around the knee (cryoneurolysis) one day before total knee replacement surgery can lower pain and help patients move better afterward. About 100 adults with knee arthritis will be randomly assigned to get the freezing procedure plus surgery…

This study tests a new exercise program using a flywheel device to improve stair-climbing in people with knee osteoarthritis. The training focuses on the muscle-lengthening phase of movement, which may build better muscle and coordination. Researchers will measure changes in move…

This study looks at how the quality and movement of thigh muscles relate to pain, daily function, and quality of life in women with knee osteoarthritis. About 58 women aged 40-70 will have a painless ultrasound of their thigh muscles and fill out questionnaires. The goal is to be…

This study will compare women with knee osteoarthritis who also have lipedema (a fat tissue disorder) to those without lipedema. Researchers will use ultrasound to measure knee cartilage thickness and questionnaires to assess pain and daily function. The goal is to understand if …