Laser vs. standard therapy: which eases knee arthritis pain better?
NCT ID NCT07551245
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether high-intensity laser therapy (HILT) plus exercise works better than standard physical therapy plus exercise for knee osteoarthritis. One hundred adults aged 40 to 75 with knee arthritis will be split into two groups to compare pain relief, joint function, and knee health over time. The goal is to find a more effective way to reduce pain and improve daily movement without surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosis of Knee Osteoarthritis: Patients must have a clinical and radiographic diagnosis of knee OA according to the American College of Rheumatology (ACR) criteria, including evidence of joint space narrowing, osteophyte formation, and other degenerative changes observed on X-rays or MRI. Age: Adults aged between 40 and 75 years. Willingness to Participate: Participants must provide informed consent and be willing to adhere to the study protocol, including attending all treatment sessions and follow-up assessments. Kellgren-Lawrence Grade: Patients with knee OA grades 1-3 (mild to moderate OA). Exclusion Criteria: * Contraindications to Laser Therapy: Active malignancy History of epilepsy Photosensitivity disorders Active infection in the treatment area Surgical History: Patients who have undergone knee surgery within the past 6 months Scheduled surgery during the study period Advanced Disease: Kellgren-Lawrence Grade 4 (severe OA) where surgical intervention is indicated Pregnancy or Lactation: Pregnant or lactating women Severe Comorbidities: Uncontrolled diabetes Severe cardiovascular disease Neurological disorders that might interfere with participation or affect treatment outcomes
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Aylan Center
RECRUITINGErbil, Erbil Governorate, 44001, Iraq
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Thigh muscle clues may predict who gets knee pain relief
- Talking through pain: could counseling unlock better exercise for knee arthritis?
- Can education boost exercise compliance for chronic pain sufferers?
- Could a simple X-Ray measurement outperform BMI in knee surgery safety?
- Can sound waves soothe aching knees?