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Thigh muscle ultrasound may predict knee OA disability

NCT ID NCT07541274

Knowledge-focused Sponsor: Izmir City Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 26, 2026 · Updated 2 times

Summary

This study looks at how the quality and movement of thigh muscles relate to pain, daily function, and quality of life in women with knee osteoarthritis. About 58 women aged 40-70 will have a painless ultrasound of their thigh muscles and fill out questionnaires. The goal is to better understand how muscle health impacts symptoms, which could guide future treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 58 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Female patients aged 40-70 years diagnosed with knee osteoarthritis (OA) who apply to the Physical Medicine and Rehabilitation Clinic of Izmir City Hospital will be screened according to the study criteria. Individuals diagnosed clinically and radiographically with Kellgren-Lawrence Grade 2-3 knee osteoarthritis, who are capable of performing isometric quadriceps contractions, and who volunteer to participate in the study will be included after signing the informed consent form.

Ages

40 to 70 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female sex * Aged between 40 and 70 years * Diagnosed with clinical and radiographic primary knee osteoarthritis (Kellgren-Lawrence Grade 2 or 3) * Ability to perform isometric contraction at 90° of knee flexion * Voluntary participation and provision of written informed consent Exclusion Criteria: * History of knee surgery within the last 6 months * Intra-articular injection (e.g., corticosteroids, hyaluronic acid) within the last 3 months * Presence of inflammatory rheumatic diseases (e.g., Rheumatoid Arthritis, Spondyloarthropathy) * Known neuromuscular disorders affecting the lower extremities * Severe cardiopulmonary comorbidities that prevent participation in clinical assessments * Severe patellofemoral instability

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Conditions

The condition(s) this trial relates to.

Knee Injuries osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee arthritis, osteoarthritis Osteo arthritis of the knee

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Izmir Cıty Hospital

    RECRUITING

    Izmir, Bayraklı/izmir, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.