Balance training may be key to softer knees
NCT ID NCT07653841
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of balance and strength exercises added to standard physical therapy for knee osteoarthritis. Sixty adults aged 40-70 with mild to moderate knee arthritis will be randomly assigned to one of two exercise programs. The goal is to see which approach better reduces pain and improves daily function over the course of treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Perturbation-Based Balance Training and Progressive Neuromuscular Training
- What this could lead to
- If successful, this could offer a simple, drug-free exercise option to reduce knee pain and improve mobility for people with mild to moderate osteoarthritis.
- What could go wrong
- This is a small, early-stage trial with only 60 participants. The exercises may not provide lasting relief or work for everyone, and results may not apply to people with severe arthritis.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Male and female, aged between 40-70 years Diagnosed with knee osteoarthritis Grades I-III based on the Kellgren-Lawrence classification Chronic knee pain for ≥3 months Ability to walk independently Exclusion Criteria: Grade IV osteoarthritis Previous knee surgery or joint replacement Rheumatoid arthritis or inflammatory joint disease Recent intra-articular injection (\<6 months) Severe systemic illness, Neurological disorders and Vestibular disorders
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Institute of Medical Rehabilitation (IMR)
RECRUITINGIslamabad, ICT, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Thigh muscle clues may predict who gets knee pain relief
- Talking through pain: could counseling unlock better exercise for knee arthritis?
- Can education boost exercise compliance for chronic pain sufferers?
- Could a simple X-Ray measurement outperform BMI in knee surgery safety?
- Can sound waves soothe aching knees?