HEALTHY ADULT PARTICIPANTS

This study looked at whether adding probiotics or antibiotics to standard non-surgical gum disease treatment helps improve gum health. Sixty adults with severe periodontitis took part. The goal was to see if probiotics could reduce the need for antibiotics, which can have side ef…

This study tested whether using a laser instead of a scalpel for gum surgery reduces pain and discomfort. 36 healthy adults with missing teeth and shrunken jawbones took part. The results showed that laser-treated areas caused significantly less pain and discomfort than the tradi…

This study looked at whether a single session of roller massage could lower blood pressure in healthy young adults. Researchers measured changes in tissue hardness and blood pressure after massage. The goal was to understand how massage might affect the body's blood pressure cont…

This study looked at how wearing minimalist (barefoot-style) shoes for a long time affects foot health in healthy adults. Researchers compared 90 people split into two groups: one wore minimalist shoes, the other wore regular shoes. They measured foot muscle size, balance, pressu…

This study tested whether a mobile app called Stressometer can help healthy university students track their stress levels four times a day for two weeks. Researchers wanted to see if students would use the app regularly and if the stress scores matched results from standard quest…

This early-stage study tested a new oral drug called ARN-75039, being developed to treat Lassa fever, a serious viral illness. The trial involved 94 healthy adults to check the drug's safety and how the body processes it. Participants received either the drug or a placebo in sing…

This early-stage trial tested the safety and how the body handles a new drug called TBD09. 36 healthy adults took either TBD09 or a placebo daily for up to 84 days. The main goal was to check for side effects and measure drug levels in the blood. This study does not aim to treat …

This early-stage study tested a new drug, PORT-77, in 156 healthy adults to see if it is safe and how the body processes it. Participants received either the drug or a placebo, and researchers monitored for side effects and drug levels in the blood. The goal was to gather initial…

This study involved 44 healthy adults to see if taking two 164.4 mg capsules of centanafadine once daily is equivalent to taking one 328.8 mg capsule. The goal was to measure drug levels in the blood, not to treat any disease. Participants were in good health and received both do…

This early-stage trial tested the safety and tolerability of a new drug called TBD11 in 124 healthy adults. Participants received either the drug or a placebo, and researchers monitored for side effects and how the drug moves through the body. The study did not aim to treat any d…

This study looked at how the experimental drug PF-07248144 is absorbed, processed, and removed from the body. Eight healthy adults received a radiolabeled version of the drug by mouth and by IV. Researchers measured the drug in blood, urine, and stool to understand its movement a…

This study looked at whether eating three apples a day for three days changes the activity of gut bacteria in healthy adults. Researchers collected stool samples before and after the apple-eating period and analyzed them for metabolic byproducts. The goal was to see if short-term…

This study looked at how a single session of whole-body cold water immersion changes stress hormones, immune cells, and other body chemicals in healthy young adults. 41 volunteers were monitored over two days. The goal was simply to observe these changes, not to treat any disease…

This study looked at how the drug vorasidenib changes the way the body processes several common medications. Twenty-eight healthy adults took the medications alone and then again with vorasidenib. The goal was to see if vorasidenib affects drug levels, which helps doctors decide …