HEALTHY ADULT PARTICIPANTS

This study tests a new medicine called CPV-104 for the first time in people. It is designed to calm an overactive part of the immune system that causes damage in C3 glomerulopathy (C3G), a rare kidney disease. The trial includes healthy adults and people with C3G to check safety,…

This study tests a smartphone-based program designed to improve REM sleep quality. Researchers want to see if better REM sleep can help healthy adults feel less stressed, manage emotions better, and enjoy a higher quality of life. The study will involve 360 participants who will …

This study tests a new nasal spray called RIG-101 in two parts. First, it checks safety in healthy people and adults with asthma. Second, it sees if the spray can reduce asthma symptoms when participants are exposed to a common cold virus. The goal is to find a safe way to preven…

This study tests a new drug called BGB-45035 for the first time in humans. It will check safety and how the body processes the drug in healthy volunteers, then test it in people with autoimmune skin diseases like eczema and prurigo nodularis. The goal is to see if the drug is saf…

This study is testing a Turkish version of a tool called PRoTECT, which measures how much parents and future parents know about toxic chemicals in the environment and how those chemicals can affect children's development. Researchers will enroll 204 healthy adults to check if the…

This study looks at how eating kimchi (fermented cabbage) affects the gut health of healthy adults. Researchers will compare people who eat kimchi daily with those who eat plain cabbage daily for 3 weeks. They will measure changes in gut bacteria, digestion markers, and heart hea…

This study tests a new, non-invasive brain stimulation technique called transcranial temporal interference stimulation (TIS) in 30 healthy adults aged 18-65. The goal is to understand how TIS works by measuring its effects on brain activity using another technique called transcra…

This early-stage study looks at whether a new drug called BV100 changes how the body handles another drug, polymyxin B. It involves 16 healthy adults who will receive both drugs in a set order. The goal is to measure drug levels and check for side effects, not to treat any diseas…

This study looks at how stopping smoking for six weeks affects the body's chemistry and gut bacteria in people with substance use disorders. Researchers will compare 100 participants who quit smoking with 50 healthy controls, using blood and stool samples along with psychological…

This study is the first time ADX-626 is being tested in humans. It aims to check the drug's safety and how the body handles it in 44 healthy adults aged 18 to 45. Participants will receive either the drug or a placebo. This study does not aim to treat any disease.

This study is testing a new radioactive tracer called [18F]GATT-44 to see how well it can image GABA transporters in the brain using PET scans. It involves 32 healthy adults aged 18 to 60. The goal is to measure how the tracer moves through the body and binds to brain targets, an…

This study tests whether a new generic selegiline skin patch works the same as the brand-name EMSAM patch in 92 healthy adults. Researchers will measure how much drug gets into the body and how well the patch sticks to the skin over 24 hours. The goal is to show the generic versi…

This study looks at whether breathing slowly (6 breaths per minute) lowers stress more than breathing at a normal pace or just sitting still. Healthy adults will practice a breathing method, then take a stress test involving cold water and math. Researchers will measure heart rat…

This early-phase study tests the safety of a new drug called MTX-439 in healthy adults and people with diabetic kidney disease. Researchers will give single or multiple doses to see how the body handles the drug and what side effects occur. The study does not aim to treat the dis…

This early-stage study in 60 healthy Chinese adults checks how the drugs itraconazole, rifampin, and midazolam change the levels of a new medicine called SIM0270 in the body. Participants take SIM0270 alone and with each other drug to see if there are any interactions. The study …

This study explores how a safe, mild electrical current applied to the scalp (transcranial random noise stimulation) affects language performance. Healthy adults aged 18-35 or 60-90 will do language tasks during real or fake stimulation, without knowing which. The goal is to lear…

This study tests a robot called Regen that helps physical therapists guide patients during walking therapy. Ten healthy adults aged 18-50 will walk on a treadmill while the robot assists their leg movements. Researchers will measure how easy and safe the robot is to use, and how …

This study looks at what happens when young adults drink Jägerbombs (a mix of energy drink and alcohol) compared to drinking alcohol alone during a binge-drinking session. Researchers will measure changes in reaction time, coordination, vision, and hangover symptoms. The goal is …

This study looks at how runners' emotions and coping strategies change during an 80-kilometer ultra-endurance race and how these factors affect their performance and fatigue. Researchers will track 80 healthy adult participants before, during, and after the race using surveys and…

This study looks at how runners' minds handle a very long, 120-kilometer race. Researchers want to understand how people's emotional habits and coping styles affect their feelings, tiredness, and performance during the race. About 80 healthy adults who are already signed up for t…

This early-stage study is testing a new drug, ALXN2230, in 48 healthy adults to see if it is safe and how the body processes it. Participants receive a single injection of either the drug or a placebo. The study tracks side effects, drug levels in the blood, and immune responses.