Oil pulling mouthwash put to the test for brighter smiles
NCT ID NCT07667088
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a natural oil pulling mouthwash (GuruNanda) can whiten teeth better than a standard whitening mouthwash or a placebo. 120 healthy adults will use one of three rinses nightly for a period. Researchers will measure tooth shade and stain levels using special devices and visual checks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- GuruNanda natural Oil Pulling oral rinse (dietary supplement)
- What this could lead to
- If it works, this could offer a natural alternative for tooth whitening without harsh chemicals.
- What could go wrong
- This is a small, early-stage trial with no blinding, so results may not be reliable. The effect may be minimal or no better than a placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Adult subjects aged 18-60, that are in good health. 2. Subject must have at least 2 natural anterior teeth, each having a mean Lobene composite score of ≥ 1.5 on the facial surfaces as assessed by the Investigator. 3. Subject's front teeth shade should be 9 or darker (meaning shade score should be between 9 and 29), as assessed by the Vita bleachguide 3D-Master and the Vita EasyShade device. 4. Subjects should understand the information provided about the investigative nature of the treatment, possible benefits and side effects. Subjects will sign the Informed Consent Form. 5. The subjects should be willing to comply with the study procedure and schedule, including the follow up visits, and will refrain from using any other teeth whitening technologies during this period. 6. The subject did not perform any procedure for teeth whitening (either at home or in clinic) at least 3 years prior to participating in the study. Exclusion Criteria: 1. Pregnant or nursing by subject report. 2. Known allergic reaction to any of the study mouthwashes or any of their components. Participant has completed the screening questionnaire (Exclusion due to Known Allergens). 3. Any active condition in the oral cavity at the discretion of the investigator. 4. Any surgery or dental procedure in the treated area within 3 months prior to treatment, or before complete healing. 5. Subjects that do not brush regularly. 6. Any condition that might make it unsafe for the subject to participate in the study, at the discretion of the investigator. 7. Heavy tobacco use, including cigarettes, cigars, or smokeless tobacco. 8. Consumption of stain-causing substances (e.g., red wine, coffee, tea) that cannot be avoided during the study period. 9. Use of medications that may affect tooth discoloration (e.g., tetracyclines, chlorhexidine). 10. Participation in another clinical trial within the last 30 days. 11. Presence of orthodontic appliances, except for removable retainers. 12. Signs of advanced enamel wear, dentin exposure, or tooth fractures.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Clinical Research Facility of the Center for Oral Health and Research, UTHSA
RECRUITINGSan Antonio, Texas, 78229, United States
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