GLIOBLASTOMA MULTIFORME

This study tested a device called Optune that delivers electric fields to the brain, combined with radiation and chemotherapy, in nearly 1,000 adults with newly diagnosed glioblastoma (a fast-growing brain cancer). The goal was to see if adding Optune to standard treatment helps …

This small pilot study tested whether adding a focused ultrasound device (NaviFUS) to standard chemotherapy (bevacizumab) could help control recurrent glioblastoma, an aggressive brain cancer. Six adults whose cancer returned after prior treatment took part. The main goals were t…

This early-phase study tested a new drug called tinostamustine in 10 people with a fast-growing brain cancer (glioblastoma) that has a specific genetic marker (unmethylated MGMT). The goal was to find a safe dose and see how the drug works after standard treatment. Participants r…

This study looked at whether a modified Atkins-based diet combined with short-term fasting is possible for people with glioblastoma, an aggressive brain cancer. Twenty-five patients who had already completed standard treatments tried the diet for 8 weeks. The goal was to see if t…

This early-stage study tested an experimental drug called INCB7839 in 13 children whose high-grade gliomas (aggressive brain tumors) had come back or worsened after standard treatment. The main goals were to find a safe dose and identify side effects. The study was completed, but…

This early-phase study tested whether adding chlorpromazine, a medication used for mental health conditions, to standard chemotherapy and radiation is safe for people with newly diagnosed glioblastoma, an aggressive brain cancer. Ten adult patients participated to find the best d…

This study tested a drug called VAL-083 combined with standard radiation for people newly diagnosed with a fast-growing brain cancer (glioblastoma) that has a specific genetic marker (unmethylated MGMT). The goal was to find a safe dose and see if the combination helps control th…

This study looked at whether giving a second round of radiation is safe for people whose glioblastoma (a fast-growing brain tumor) has come back after standard treatment. Seventeen adults aged 18 to 50 with good overall health took part. The goal was to find the highest safe dose…

This study tested whether a special type of scan (FET-PET/MRI) can more accurately show the full extent of glioblastoma brain tumors after surgery compared to standard MRI. The goal was to see if this could help doctors plan radiation treatment better, potentially improving survi…

This study looked at 33 adults with glioblastoma, a fast-growing brain cancer, whose tumors worsened soon after surgery. Researchers used a special PET scan with 11C-methionine to see tumor activity better than standard MRI. The goal was to adjust radiation plans based on this ex…