GLIOBLASTOMA MULTIFORME

This early-stage study tested a new oral drug called INCB7839 in children whose aggressive brain tumors had returned or worsened after standard treatments. The main goals were to find the highest safe dose and understand how the drug moves through the body. Researchers hoped the …

This study tested a drug called VAL-083, given alongside standard radiation therapy, for people newly diagnosed with an aggressive brain cancer called glioblastoma (GBM). It focused on patients whose tumors have a specific genetic feature (unmethylated MGMT) that makes them less …

This study tested whether a special diet could help control glioblastoma, an aggressive brain cancer. Researchers had 25 patients who had finished initial treatment try a low-carbohydrate diet combined with short fasting periods. The goal was to see if this diet was practical to …

This study tested the safety of giving a second course of radiation to people whose aggressive brain tumor (glioblastoma) had grown back after initial treatment. The main goal was to find the highest dose of repeat radiation that patients could tolerate without severe side effect…

This was a small, early-stage study to test the safety and dosing of a new drug called tinostamustine for a type of brain cancer called glioblastoma. It involved 10 adults who had recently finished standard radiation and chemotherapy. The main goal was to find the highest dose pa…

This small, early-stage study tested whether adding a low dose of an old psychiatric drug called chlorpromazine to the standard treatment for a fast-growing brain cancer (glioblastoma) is safe. Ten adults with newly diagnosed cancer received the drug combination alongside radiati…

This study tested a special type of PET scan to see if it could improve treatment for patients with an aggressive form of brain cancer called glioblastoma. The scan uses a radioactive tracer called 11C-methionine to get a clearer picture of where the fast-growing tumor cells are …

This study tested whether a newer type of brain scan (FET-PET/MRI) could more accurately map the remaining tumor after surgery compared to the standard MRI scan. The goal was to see if this could help doctors better target radiation therapy, potentially improving treatment effect…