New hope for aggressive brain cancer? early trial tests tinostamustine
NCT ID NCT05432375
First seen Jan 03, 2026 · Last updated May 24, 2026 · Updated 25 times
Summary
This early-phase study tested a new drug called tinostamustine in 10 people with a fast-growing brain cancer (glioblastoma) that has a specific genetic marker (unmethylated MGMT). The goal was to find a safe dose and see how the drug works after standard treatment. Participants received the drug once every three weeks for up to 12 cycles, and researchers monitored side effects and tumor response.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hospital Universitario Ramón y Cajal, Madrid, Spain
Madrid, Spain
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Hospital Universitario Vall d'Hebron, Barcelona, Spain
Barcelona, Spain
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Kantonsspital
Sankt Gallen, Switzerland
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South Texas Accelerated Research Therapeutics (START)
Madrid, Spain
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University Hospital
Zurich, Switzerland
Conditions
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