New scan could sharpen radiation for Fast-Growing brain cancers
NCT ID NCT05608395
First seen Oct 01, 2025 · Last updated Jun 22, 2026 · Updated 35 times
Summary
This study tested whether a PET/CT scan using 11C-methionine, a radioactive amino acid, could improve radiotherapy planning for people with glioblastoma (a fast-growing brain cancer) whose tumors worsen soon after surgery. Thirty-three patients received the scan before starting chemo-radiation, and their outcomes were compared to a historical group. The goal was to see if this extra imaging leads to better survival by targeting the tumor more accurately.
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Masaryk Memorial Cancer Institute
Brno, Czech Republic, 65653, Czechia
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
11C-methionine (a radioactive amino acid used in PET/CT scans)
What this could lead to
If successful, this imaging technique could help doctors create more precise radiotherapy plans for aggressive brain tumors, potentially improving survival.
What could go wrong
This is a small, early-phase study with only 33 participants. The benefit over standard MRI-based planning is not yet proven, and the radioactive tracer may not significantly change outcomes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.