Surgical flap opens door to brain tumors in small safety trial
NCT ID NCT03630289
First seen Jun 16, 2026 · Last updated Jun 23, 2026 · Updated 3 times
Summary
This study tested a new surgical technique in 12 patients with newly diagnosed glioblastoma, an aggressive brain cancer. Surgeons placed a tissue flap from the scalp into the brain tumor cavity to bypass the blood-brain barrier, which normally blocks many treatments. The main goal was to check safety, and researchers also looked at whether it might help patients live longer without the tumor growing.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Lenox Hill Brain Tumor Center
New York, New York, 10075, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
surgical tissue flap (temporoparietal fascial or pericranial flap)
What this could lead to
If successful, this technique could allow better delivery of future treatments directly to the brain tumor, potentially improving survival for glioblastoma patients.
What could go wrong
This was a very small, early safety study with only 12 participants. The procedure carries risks like infection, stroke, or seizures, and it is not yet known if it truly helps patients live longer.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.