GLIOBLASTOMA MULTIFORME

This study looked at whether a modified Atkins-based diet combined with short-term fasting is possible for people with glioblastoma, a serious brain cancer. Twenty-five patients who had already completed standard treatment tried the diet for 8 weeks. The goal was to see if they c…

This study tested a drug called VAL-083 combined with standard radiation in 29 adults with a newly diagnosed, aggressive brain cancer (glioblastoma) that has a specific genetic marker (unmethylated MGMT). The goal was to find the safest dose and see if the combination shrinks tum…

This early-phase study tested a drug called INCB7839 in 13 children whose high-grade gliomas (aggressive brain tumors) had come back or worsened after standard treatment. The main goal was to find a safe dose and check for side effects. The drug works by blocking a protein that h…

This early-phase study tested a new drug called tinostamustine in 10 people with a fast-growing brain cancer (glioblastoma) that has a specific genetic marker (unmethylated MGMT). The goal was to see if the drug is safe and how the body processes it, given after standard treatmen…

This early study tested a device called NaviFUS that uses focused ultrasound waves, combined with the standard drug bevacizumab, in 6 adults whose glioblastoma brain tumor had come back after prior treatment. The goal was to see if the combination was safe and could help control …

This study tested whether a special type of scan (FET-PET/MRI) can better show the full extent of glioblastoma brain tumors after surgery compared to standard MRI. The goal was to see if this could help doctors plan radiation treatment more accurately. Eleven adults who had surge…

This study looked at 33 adults with glioblastoma, an aggressive brain cancer, whose tumors grew quickly after surgery. Researchers used a PET scan with a radioactive amino acid called 11C-methionine to see the active tumor better than standard MRI. The goal was to use this extra …