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New hope for aggressive brain cancer: early trial tests tinostamustine

NCT ID NCT05432375

First seen Jan 03, 2026 · Last updated Apr 29, 2026 · Updated 23 times

Summary

This early-phase study tested a new drug called tinostamustine in 10 people with a fast-growing brain cancer (glioblastoma) that has a specific genetic marker (unmethylated MGMT). The goal was to see if the drug is safe and how the body processes it, given after standard treatment. While it aims to control the disease, it is not a cure, as ongoing monitoring and potential further treatment are needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital Universitario Ramón y Cajal, Madrid, Spain

    Madrid, Spain

  • Hospital Universitario Vall d'Hebron, Barcelona, Spain

    Barcelona, Spain

  • Kantonsspital

    Sankt Gallen, Switzerland

  • South Texas Accelerated Research Therapeutics (START)

    Madrid, Spain

  • University Hospital

    Zurich, Switzerland

Conditions

Explore the condition pages connected to this study.