GENERALIZED ANXIETY DISORDER

This study tests an oral medication called MM120 against a placebo in 250 adults with generalized anxiety disorder. The first 12 weeks are double-blind (neither patients nor doctors know who gets the real drug), followed by a 40-week period where everyone can receive MM120. The m…

This study is for people who have both an anxiety disorder and an alcohol use disorder. It tests whether a computer-based therapy can help reduce heavy drinking and improve anxiety symptoms. The program is designed to be easy to access and use, potentially helping many more peopl…

This study tests a new medicine called crisugabalin for people with generalized anxiety disorder. About 216 adults in China will take either crisugabalin, a placebo, or another anxiety drug (venlafaxine) for 8 weeks. The goal is to see if crisugabalin reduces anxiety symptoms bet…

This study tests an oral medication called MM120 for adults with generalized anxiety disorder. About 200 participants will receive either MM120 or a placebo for 12 weeks, followed by a 40-week period where everyone can receive MM120. The goal is to see if MM120 reduces anxiety sy…

This study is testing a new internet-based therapy for young people aged 8 to 17 with anxiety disorders. The therapy is a type of talk therapy called cognitive behavioral therapy (CBT) delivered online. The goal is to see if it reduces anxiety and to get feedback from participant…

This study tests a new, non-invasive treatment for people with generalized anxiety disorder who haven't gotten better with standard medications. The treatment uses low-intensity focused ultrasound to gently stimulate a deep brain area linked to anxiety. Researchers will measure a…

This study tests an experimental medication called ITI-1284 in adults with generalized anxiety disorder (GAD) who still have symptoms despite trying other treatments. About 570 participants will receive either ITI-1284 or a placebo, added to their usual care. The goal is to see i…

This study looks at whether Swedish massage or light touch can reduce anxiety symptoms in people with Generalized Anxiety Disorder (GAD). About 46 adults will receive either massage or light touch twice a week for 6 weeks. Researchers will use brain scans (fMRI) and questionnaire…

This study compares two approaches to treating anxiety in children and teens aged 8 to 17. In stepped care, everyone starts with internet therapy and gets in-person sessions only if needed. In stratified care, the type of therapy is chosen based on how complex the case is. The go…

This study is testing whether a simple carbon dioxide (CO2) breathing challenge can help doctors predict which patients with anxiety, OCD, PTSD, or panic disorder will not respond to exposure-based therapy. Researchers will enroll 600 adults aged 18-70 and measure their response …