FUNCTIONAL DYSPEPSIA

This study aims to help children aged 11-18 with gut-brain disorders like cyclic vomiting and functional dyspepsia. These conditions cause severe nausea, vomiting, and other symptoms, and are often linked to a poorly regulated autonomic nervous system. Researchers will test a per…

This study tests whether ketotifen, a medicine that stabilizes certain immune cells, can reduce stomach pain in children aged 8-17 with functional dyspepsia (long-term stomach discomfort) and high levels of eosinophils (a type of white blood cell) in their gut. About 40 children …

This study tests if stimulating specific points on the ear can improve stomach discomfort and sleep in people with functional dyspepsia (chronic indigestion) and insomnia. Researchers will enroll 176 adults and measure symptom relief after 2 and 8 weeks. The goal is to find a saf…

This study tests whether a probiotic called Clostridium butyricum can improve anxiety and depression in people with functional dyspepsia (a stomach disorder with no clear cause). 180 adults will receive either the probiotic or a placebo for 4 weeks, alongside standard stomach med…

This study tests whether a gentle nerve stimulation device, used daily at home, combined with weekly support therapy sessions, can reduce stomach-related anxiety and improve digestion in people with functional dyspepsia. About 80 adults aged 18-65 with this condition will partici…

This study looks at whether using press needles (tiny needles taped to the skin) on body and ear acupuncture points, along with regular medication, can reduce symptoms and improve quality of life for people with functional dyspepsia (chronic stomach discomfort without a clear cau…

This study looks at whether a yoga program is practical and helpful for people with functional dyspepsia or gastroparesis—conditions that cause nausea, vomiting, and stomach pain. Ten adults will try yoga sessions and report how they feel. The goal is to see if yoga can ease symp…

This study tests whether a probiotic called Bacillus coagulans can improve anxiety and depression in people with functional dyspepsia (a stomach disorder with no clear cause). About 180 adults will receive either the probiotic or a placebo for 4 weeks, alongside standard stomach …

This study tests whether a daily supplement containing two types of probiotics and ginger extract can reduce stomach symptoms and improve quality of life in adults with functional dyspepsia—a condition causing fullness, early fullness, and upper belly pain. About 198 participants…

This study tests whether an extract from the Dolichos lablab plant (EDL) can reduce stomach symptoms in adults with functional dyspepsia—a condition causing fullness, pain, or burning without a clear cause. About 100 participants will take EDL or a placebo for 12 weeks. The goal …

This study tests whether two medications, amitriptyline and trifluoperazine, can reduce stomach symptoms like pain, fullness, and burning in people with functional dyspepsia. About 120 adults will take one of the drugs or standard treatment for 8 weeks, then be followed for 4 mor…

This study tests two digital treatments for children aged 8-17 with long-lasting stomach pain caused by gut-brain interaction issues. After a short online education program, participants are randomly assigned to either internet-based cognitive behavioral therapy (iCBT) or gut-dir…

This study tests whether using virtual reality can reduce stomach pain and other digestive symptoms in people with functional dyspepsia. About 30 adults with this condition will try VR sessions and report their symptom changes. The goal is to see if VR offers a safe, drug-free wa…

This study tests a type of talking therapy (exposure-based CBT) for adults who have both functional dyspepsia (stomach pain or fullness after eating) and avoidant/restrictive food intake disorder (ARFID) with weight loss. The goal is to see if the therapy helps people eat more co…

This study looks at how three different diets—low FODMAP, gentle FODMAP, and standard dietary advice—affect gut bacteria, gut barrier function, and symptoms in people with functional gastrointestinal disorders like IBS and functional dyspepsia. About 60 adults will follow one of …

This study looks at body composition—fat mass, muscle mass, and phase angle—in women with functional dyspepsia (a stomach disorder with no clear cause) compared to healthy women. Researchers will use a simple, non-invasive device called bio-electrical impedance analysis (BIA) to …

This study looks at how chronic atrophic gastritis (a condition where the stomach lining thins) is linked to symptoms of functional dyspepsia (persistent indigestion). Researchers will compare symptom patterns in 315 adults with and without confirmed stomach lining changes. The g…

This study aims to find out how many relatives of people with celiac disease have wheat sensitivity or other gut problems like irritable bowel syndrome. Researchers will ask 600 adult relatives to follow a wheat-free diet for 6 weeks and report their symptoms. The goal is to bett…