Could probiotics and ginger soothe chronic stomach pain?
NCT ID NCT07212907
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a daily supplement containing two types of probiotics and ginger extract in 198 adults with functional dyspepsia, a condition causing stomach pain, fullness, and burning. Participants take one capsule daily for 8 weeks. Researchers will measure changes in symptom severity and quality of life using standard questionnaires.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- probiotics (Bacillus coagulans MY01 and Bacillus subtilis MY02) and ginger extract
- What this could lead to
- If it works, this could offer a natural, non-drug option to reduce stomach discomfort and improve daily life for people with functional dyspepsia.
- What could go wrong
- This is a small, early-stage study with no placebo group, so results may not be definitive. The supplement may not work for everyone, and individual responses can vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 198 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Dec 2025
- Expected to finish
-
Jan 2027
An estimate. End dates often move.
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults (male or female) aged ≥18 years. * Diagnosis of functional dyspepsia (FD) according to Rome IV criteria, with normal upper endoscopy including negative Helicobacter pylori test. Rome IV criteria define FD as the presence of one or more of the following symptoms: bothersome postprandial fullness, early satiety, epigastric pain, or epigastric burning, occurring at least 3 days per week during the last 3 months, with symptom onset at least 6 months prior to diagnosis. * PAGI-SYM total score \>1 at baseline. * Ability to comply with study requirements and provide signed written informed consent before any study-related procedures. * Ability to complete the patient diary and questionnaires, in the investigator's opinion (sufficient reading and language comprehension). * For women of childbearing potential : Negative urine pregnancy test immediately before starting study product ; Agreement to use an approved method of contraception for the duration of the study, unless meeting criteria for menopause (≥12 months of spontaneous amenorrhea). Women of childbearing potential are defined as all women physiologically capable of becoming pregnant, including those whose career, lifestyle, or sexual orientation normally precludes heterosexual intercourse. * Affiliation with a national health insurance or social security system. Exclusion Criteria: * Use within 2 weeks prior to baseline of treatments that could interfere with study evaluation, including Bacillus coagulans MY01, Bacillus subtilis MY02, ginger, peppermint, or antibiotics. * Known allergy or hypersensitivity to any component of the investigational product. * Contraindication or specific warning related to the investigational product, including use of anticoagulants. * Use of immunosuppressive therapy within the last 3 months. * Use of medications affecting gastrointestinal motility or sensitivity, including opioids, GLP-1 analogs, neuroleptics, antiemetics, or anticholinergics. (Stable antidepressant therapy allowed.) * Significant changes in diet or physical activity within 2 weeks prior to baseline or anticipated during the study period. * Active somatic or psychiatric disorder that could explain dyspeptic symptoms (e.g., active cancer, inflammatory disease). Stable use of one antidepressant is allowed for psychiatric indication. * Active Helicobacter pylori infection. * Predominant symptoms of gastroesophageal reflux disease (GERD) or irritable bowel syndrome (IBS). * Functional diarrhea or functional constipation as defined by Rome IV criteria. * History of abdominal surgery within the past year, except appendectomy, cholecystectomy, inguinal hernia repair, or splenectomy. * Pregnant or breastfeeding women. * Individuals under legal guardianship or curatorship. * Participation in another interventional clinical trial and receipt of an investigational product within 30 days prior to baseline. * Any acute or chronic medical or psychiatric condition that, in the investigator's judgment, could interfere with study assessments, including but not limited to severe hepatic or renal insufficiency, immunodeficiency, or substance abuse (alcohol or drugs). * Any personal condition or circumstance that, in the investigator's judgment, would make full participation in the study unlikely or impossible.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Functional dyspepsia are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Gerard DASSA
RECRUITINGIstres, 13800, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a nickel allergy explain your Child's stomach pain?
- Can a pudding snack reveal how the brain misreads the stomach?
- Beyond h. pylori: a hidden stomach bacteria may influence cancer risk
- Wheat sensitivity linked to fatty liver? a new study investigates
- Ancient herbal mix targets dual gut disorders in one shot
- Digestive health mystery: study seeks to uncover hidden burden of stomach pain in rural bangladesh