FUNCTIONAL DYSPEPSIA

This study is testing a personalized approach to help children with chronic nausea, vomiting, and related symptoms like dizziness and fatigue. Researchers will use a new software to measure a child's nervous system activity in real-time and adjust a gentle ear-based nerve stimula…

This study is testing if a medication called ketotifen can help children and teenagers who have ongoing stomach pain (functional dyspepsia) linked to high levels of certain immune cells in their gut. Participants will try both ketotifen and a placebo pill in a random order to see…

This study is testing whether a combination of gentle ear stimulation and weekly support therapy can help reduce stomach pain and discomfort in people with functional dyspepsia. Participants will use a small device that stimulates a nerve in the ear while also attending weekly vi…

This study is testing if a gentle, non-drug therapy that stimulates specific points on the ear can help adults who have both chronic unexplained stomach discomfort (functional dyspepsia) and trouble sleeping. Researchers will see if this approach improves stomach symptoms and sle…

This study is testing a special type of talk therapy for adults who have chronic stomach pain (functional dyspepsia) and have developed a fear of eating, leading to significant weight loss. Researchers want to see if eight weekly video therapy sessions can help people feel more c…

This study is testing whether a seated yoga program is practical and helpful for people with functional dyspepsia or gastroparesis, conditions that cause chronic nausea and vomiting. Researchers are adapting a yoga program originally designed for cancer patients to see if it's su…

This study is testing whether two existing medications, amitriptyline and trifluoperazine, can help reduce symptoms of functional dyspepsia (chronic stomach discomfort). Researchers will compare these drugs against standard treatment in 120 adults over 12 weeks. The main goal is …

This study is testing whether using virtual reality (VR) can help reduce stomach pain and other digestive symptoms in people with functional dyspepsia. Researchers at Mayo Clinic will have 30 participants use VR to see if it eases symptoms like abdominal pain, nausea, bloating, a…

This study is testing whether a specific probiotic (Clostridium butyricum) can help reduce feelings of anxiety and depression in people who have functional dyspepsia, a common condition causing ongoing stomach pain or discomfort. The trial will involve 180 adults who will take ei…

This study is testing two online psychological treatments to help children and teenagers manage chronic stomach pain caused by gut-brain communication problems. Researchers are comparing internet-based cognitive behavioral therapy (iCBT) with gut-directed hypnotherapy delivered t…

This study is testing whether a specific probiotic supplement (Bacillus coagulans) can help reduce feelings of anxiety and depression in people who also have chronic stomach discomfort (functional dyspepsia). About 180 adults will take either the probiotic or a placebo (dummy pil…

This study is testing whether a daily dietary supplement containing specific probiotics and ginger extract can help reduce stomach pain, fullness, and discomfort in adults with functional dyspepsia. About 200 participants will take one capsule daily for 8 weeks to see if it impro…

This study is testing whether a type of acupuncture using small press needles can help people with functional dyspepsia, a condition causing ongoing stomach pain, bloating, and fullness without a clear cause. Researchers are comparing real press needles to fake ones to see if the…

This study aims to understand if people with a specific type of confirmed stomach lining damage (chronic atrophic gastritis) experience different or worse digestive symptoms than those without it. Researchers will observe about 315 adults who have had a recent stomach scope showi…

This study aims to understand if there are physical differences in body composition between women with functional dyspepsia (chronic unexplained stomach discomfort) and healthy women. Researchers will use a painless electrical scan to measure body fat, muscle mass, and other phys…