Stomach study aims to untangle indigestion mystery
NCT ID NCT07250308
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether people with a certain stomach lining condition (chronic atrophic gastritis) have different indigestion symptoms than those without it. Researchers will compare symptom patterns in about 315 adults who recently had an endoscopy. The goal is to better understand the link between these conditions and improve how doctors diagnose and manage symptoms.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 315 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients (aged 18-75 years) with endoscopic findings suggestive of chronic atrophic gastritis within the past 12 months at the Third Affiliated Hospital of Zhejiang Chinese Medical University. Target enrollment: 258-315 patients to ensure at least 80 pathologically confirmed non-CAG cases. Eligible patients undergo endoscopy for dyspeptic symptoms, surveillance, or upper abdominal discomfort. All undergo standardized 5-point gastric biopsy per Updated Sydney System for histopathological classification into CAG or non-CAG groups. Both symptomatic and asymptomatic patients are eligible; no H. pylori status restrictions. Exclusions: organic GI diseases (peptic ulcer, gastric cancer, IBD), autoimmune gastritis, severe systemic diseases, inability to consent. Consecutive recruitment from routine clinical practice ensures representative sampling.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age 18-75 years 2. Recent gastroscopic examination (within 1 year) suggesting chronic atrophic gastritis 3. Underwent standardized pathological examination (5-point gastric mucosa biopsy according to the "Updated Sydney System" including antrum, body, and angle) 4. Signed informed consent Exclusion Criteria: 1. Gastric cancer or suspected malignant lesions 2. Concomitant significant other gastrointestinal diseases (e.g., ulcer, Barrett's esophagus, etc.) 3. Autoimmune gastritis 4. Unable to complete questionnaire survey
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The Third Affiliated Hospital of Zhejiang Chinese Medicinal University
RECRUITINGHangzhou, Zhejiang, 310053, China
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