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Gut feeling: can a probiotic lift mood in stomach disorder?

NCT ID NCT07182890

First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 33 times

Summary

This study tests whether a probiotic called Clostridium butyricum can help reduce anxiety and depression in people with functional dyspepsia (a common stomach disorder). 180 adults will receive either the probiotic or a placebo for 4 weeks, alongside standard stomach medication. The main goal is to see if mood scores improve.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Air Force Medical University

    RECRUITING

    Xi’an, Shanxi, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Clostridium butyricum (a probiotic)

What this could lead to

If it works, this could offer a simple, gut-friendly way to improve mood and stomach symptoms together.

What could go wrong

This is a small, early-phase trial. The effect may be small or no better than placebo, and results may not apply to everyone with dyspepsia.

Conditions

The condition(s) this trial relates to.

anxiety disorder Depression

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.